Effect of Stent Placement on Short Term Survival of Left Sided Obstructive Colorectal Cancers

NCT ID: NCT06437691

Last Updated: 2024-08-20

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 65 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2016-01-01
• Study Completion Date: 2024-02-20

Brief Summary

The aim of this observational study is to determine effect of stent placement on survival results in first three years in a patient who applied to the emergency department with obstruction due to colorectal cancer. Eligible patients divided into two groups. Group A includes patients underwent emergency surgery directly. Patients underwent elective surgery following stent placement as bridge-to-surgery. Patients underwent elective surgery following bridge-to-surgery stent placement were accepted as Group B.

Detailed Description

Patients who applied to emergency department of a single tertiary referral center between January 2016 and December 2020 and diagnosed as left sided obstructive colorectal cancer were included in this retrospective study. All patients were equal or older than 18 years and histopathologically found to have primary colorectal malignant neoplasms.

Patients were excluded from the analysis if they met any of the following criteria:

• Who underwent emergency surgery due to unsuccessful stent application intervention or stent-related complications developed,
• Those with middle and lower rectum tumors or received neoadjuvant treatment,
• Perforation,
• Who underwent subtotal or total colectomy (as a result of colon ischemia in the cecum, microperforation, etc.),
• Recurrent disease patients
• Patients have metastasis

Conditions

Colorectal Cancer

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: RETROSPECTIVE

Study Groups

Group A - Emergency Surgery Group

Patients underwent emergency surgery directly after coming to emergency department due to left sided obstructive colorectal cancer

No interventions assigned to this group

Group B - Stent Group

Left sided obstructive colorectal cancer patients underwent elective surgery following decompression via self-expandable metallic stent placement.

Self-Expandable Metallic Stent Placement

Intervention Type: PROCEDURE

Interventions

Self-Expandable Metallic Stent Placement

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• All patients were equal or older than 18 years and histopathologically found to have primary colorectal malignant neoplasms and diagnosed as left sided (descending colon, sigmoid colon and upper rectum) obstructive colorectal cancer were included

Exclusion Criteria

• Who underwent emergency surgery due to unsuccessful stent placement intervention
• Who underwent emergency surgery due to stent-related complications
• Those with middle and lower rectum tumors
• Those received neoadjuvant treatment,
• Patients have perforation,
• Who underwent subtotal or total colectomy (as a result of colon ischemia in the cecum, microperforation, etc.),
• Who has a recurrent disease or metastasis.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Yasir Musa Kesgin, MD

OTHER

Sponsor Role: lead

Responsible Party

Yasir Musa Kesgin, MD

MD

Responsibility Role: SPONSOR_INVESTIGATOR

Principal Investigators

Ahmet Sürek

Role: STUDY_CHAIR

Bakırköy Dr. Sadi Konuk Training and Research Hospital

Other Identifiers

StentSurv

Identifier Type: -

Identifier Source: org_study_id