PMCF Study of the CE-marked Drainova® ArgentiC Catheter

NCT ID: NCT06436807

Last Updated: 2025-03-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

162 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-06-26

Study Completion Date

2026-08-31

Brief Summary

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The goal of this observational study is to learn about the performance of the drainova® ArgentiC Catheter in clinical routine, which is used to treat fluid accumulations in hollow body structures. The device is already on the market and participants receive the catheter as part of their regular treatment.

The main questions of this study are:

* Does the device function as intended?
* Are there any other safety risks that have not been identified?
* Does it lower the symptoms of the patients as intended?

Doctors and patients will answer questions regarding the improvement of the patients´ symptoms and if there were any problems with the catheter.

Detailed Description

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The drainova® ArgentiC Catheter initially received the CE mark in 2019 under the Medical Device Directive 93/42/EEC, thus being considered a legacy device under the Medical Device Regulation (EU) 2017/745 (MDR). In order to fulfill the requirements of the MDR, this PMCF study is planned to be conducted to obtain clinical data on the device confirming its safety, performance and clinical benefit in clinical routine according to the instructions for use (IFU).

This PMCF study is performed as a purely observational activity within the current standards of care and without additional invasive or burdensome procedures. The drainova® ArgentiC catheter is a catheter indicated for the treatment of patients with pleural effusions and ascites, both in the malignant and non-malignant manifestations.

Conditions

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Pleural Effusion Pleural Effusion, Malignant Ascites Ascites, Malignant

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Indwelling catheter

The tunneled catheter is an implant product that enables the drainage of effusion accumulations from serous body cavities so that the symptoms caused by an effusion are relieved by draining off the accumulated fluids.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients ≥ 18 years old
* Patients being able to give informed consent

Exclusion Criteria

Patients with any contraindication according to the IFU:

* presence of septa in the body cavity
* coagulopathy
* infection in the body cavity
* lymphatic effusion
* shift of the mediastinum (by more than 2 cm to the ipsilateral side of the pleural effusion)
* known allergies to any of the materials used in the drainage product
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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LS medcap GmbH

OTHER

Sponsor Role collaborator

ewimed GmbH

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Heidrun Steinle, Dr

Role: STUDY_CHAIR

LS medcap GmbH

Locations

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Universitätsklinikum Augsburg

Augsburg, , Germany

Site Status RECRUITING

Charité Universitätsmedizin Berlin

Berlin, , Germany

Site Status RECRUITING

Klinikum Chemnitz gGmbH

Chemnitz, , Germany

Site Status RECRUITING

Klinikum Chemnitz gGmbH MVZ Flemmingstraße

Chemnitz, , Germany

Site Status RECRUITING

Universitätsklinikum Freiburg

Freiburg im Breisgau, , Germany

Site Status RECRUITING

Universitätsklinikum Freiburg

Freiburg im Breisgau, , Germany

Site Status RECRUITING

Medizinische Hochschule Hannover

Hanover, , Germany

Site Status RECRUITING

Universitätsklinikum Heidelberg

Heidelberg, , Germany

Site Status RECRUITING

Lungenklinik Hemer

Hemer, , Germany

Site Status RECRUITING

Clemenshospital

Münster, , Germany

Site Status RECRUITING

Krankenhaus Barmherzige Brüder

Regensburg, , Germany

Site Status RECRUITING

Universitätsklinikum Regensburg

Regensburg, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Natasa Mitrovic, MSc

Role: CONTACT

+49 7471 9849 9529

Heidrun Steinle, Dr

Role: CONTACT

+49 7471 9848 0175

Facility Contacts

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Philipp Jawny

Role: primary

Jens-Carsten Rückert, Prof. Dr. med.

Role: primary

Sven Seifert, Dr. med.

Role: primary

Ilja Kubisch, Dr. med.

Role: primary

Michael Schultheiß, PD Dr. med.

Role: primary

Mirjam Elze, Dr. med.

Role: primary

Benjamin Maasoumy, Prof. Dr. med.

Role: primary

Hauke Winter, Prof. Dr. med.

Role: primary

Stefan Welter, PD Dr. med.

Role: primary

Peter Feindt, Prof. Dr. med.

Role: primary

Hans-Stefan Hofmann, Prof. Dr. med.

Role: primary

Hans-Stefan Hofmann, Prof. Dr. med.

Role: primary

Other Identifiers

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23-079

Identifier Type: -

Identifier Source: org_study_id

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