Identification of Post-Traumatic Stress Disorder in Adult Patients With Substance Use Disorders

NCT ID: NCT06432400

Last Updated: 2025-03-13

Basic Information

• Recruitment Status: WITHDRAWN
• Clinical Phase: NA
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-12-31
• Study Completion Date: 2025-12-31

Brief Summary

The aim of this study is to show that early identification of PTSD and CPTSD would increase recognition of these disorders and facilitate diagnosis, referral and recovery.

Detailed Description

Between 61% and 81% of men and 51% to 74% of women are exposed to a traumatic event in their lifetime. These events may be brief and discrete, prolonged and/or recurrent, and may be direct or indirect. Direct or indirect exposure to traumatic events can lead to serious negative psychological consequences, including post-traumatic stress disorder (PTSD) and complex post-traumatic stress disorder (CPTSD). People exposed to complex traumatic events are at risk not only of suffering from PTSD or Complex PTSD, but also from other mental health co-morbidities, such as substance use disorders (drugs, alcohol, benzodiazepine misuse) , often associated with the repetition of situations of interpersonal violence from which it is difficult, if not impossible, to escape.

Caring for people suffering from psychological trauma is a major public health issue. However, there are no good clinical practice guidelines for diagnosis, assessment and treatment, which would enable good practice to be standardised and disseminated. The prevention, detection, early support and appropriate guidance of people suffering from post-traumatic sequelae promote their recovery and improve their quality of life. The World Health Organization (WHO) refers to this as psychological distress, and points out that if it is not properly identified or accompanied, it can tip a person into illness or increase social difficulties. When it is temporary and follows a stressful event, it is considered a normal adaptive reaction. On the other hand, when it becomes intense and persistent, it may be an indicator of a psychological disorder. The public health challenge associated with PTSD is to better recognise, diagnose and treat it, as it can have serious consequences for the quality of life, social functioning and suicide risk of those affected.

The aim of this study is to show that early identification of PTSD and CPTSD would increase recognition of these disorders and facilitate diagnosis, referral and recovery. It would also make it possible to provide individualised support for patients and improve their quality of life.

Conditions

Trauma

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Substance use disorders

Group composed of patients suffering from disorders related to the use of alcohol, cannabis, opiates, inhalants, sedatives, hypnotics, anxiolytics, stimulants, hallucinogens (all of these disorders will have been diagnosed by a doctor before or during follow-up according to Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM 5) criteria)

Group Type: OTHER

Patient questionnaires

Intervention Type: OTHER

Patients questionnaires, on paper and data collection on patients medical file

Interventions

Patient questionnaires

Patients questionnaires, on paper and data collection on patients medical file

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patient aged 18 or over
• Patient followed up at the adult Medical and Psychological Centre in the centres taking part in the study
• Patient suffering from disorders related to the use of alcohol, cannabis, opiates, inhalants, sedatives, hypnotics, anxiolytics, stimulants, hallucinogens (all of these disorders will have been diagnosed by a doctor before or during follow-up according to DSM 5 criteria).
• Patient aware of their substance use disorders
• Patient informed and did not object to participating in the study

Exclusion Criteria

• Patient previously diagnosed with PTSD or CPTSD
• Patient agitated and/or aggressive
• Patient under guardianship/curators
• Patient who do not speak or understand French

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hôpital NOVO

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Déborah DELABY

Role: PRINCIPAL_INVESTIGATOR

Isarien Hospital Centre

Locations

Medical and Psychological Centre - Novo Hospital - Site Beaumont-sur-Oise

Beaumont-sur-Oise, , France

Medical and Psychological Centre - Isarien Hospital Centre

Clermont, , France

Countries

France

Other Identifiers

2024-A00790-47

Identifier Type: OTHER

Identifier Source: secondary_id

CHRD0824

Identifier Type: -

Identifier Source: org_study_id