An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-25

Study Completion Date

2029-03-25

Brief Summary

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This study evaluates the cell and biomarkers associated with the aggressive behavior of cancer.

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Detailed Description

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PRIMARY OBJECTIVE:

I. High-resolution single-cell profiling of Cancer-associated fibroblasts (CAFs) in Human papillomavirus (HPV)+ Oropharyngeal Squamous Cell Carcinoma (OPSCC) and metastatic lymph nodes.

OUTLINE: This is an observational study.

Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.

Conditions

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Head and Neck Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Observational

Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.

Non-Interventional Study

Intervention Type OTHER

Non-interventional study

Interventions

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Non-Interventional Study

Non-interventional study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosis/disease status: New diagnosis of head and neck cancer
* Allowable type and amount of prior therapy: No prior treatment
* Age ≥ 18 years.
* Ability to understand and the willingness to sign a written informed consent.