A Comparative Study Between Anterior and Posterior Pyelotomy in Transperitoneal Laparoscopic Pyelolithotomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-01

Study Completion Date

2024-04-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Large renal pelvic stones are frequently managed with percutaneous nephrolithotomy (PCNL) but laparoscopic pyelolithotomy (LPL) can be an alternative procedure when performed by skilled surgeons to achieve excellent outcomes in terms of stone free status, operative time, postoperative kidney function, hospitalization duration, and complications.

there are two methods for LPL surgery : Transperitoneal (TLP) and Retroperitoneal (RLP).

RLP associated with shorter mean time for oral intake, and mean hospital stay after surgery.

The surgical exposure in the transperitoneal route for LP is familiar to the majority of surgeons. Also, a much larger working space is available and there are various established anatomical landmarks for performing the surgery effectively. This study introduces a modified technique that creates application of posterior pyelotomy in TLP to achieve the advantages of RLP

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Laparoscopic Cholecystectomy:

NCT04107909

Cholecystitis

UNKNOWN NA

Open Versus Laparoscopic Left Hepatic Sectionectomy

NCT03958825

Hepatolithiasis Laparoscopic Liver Resection Open Liver Resection +1 more

UNKNOWN NA

External Oblique Plane Block and Subcostal Tap Block for Laparoscopic Cholecystectomy

NCT07061262

Peripheral Nerve Block Cholecystectomy, Laparoscopic Pain After Surgery

COMPLETED NA

Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy

NCT01211743

Uncomplicated Cholelithiasis Cholecystectomy Laparoscopy +2 more

COMPLETED PHASE4

Single Incision Laparoscopic Cholecystectomy Compared with Conventional Laparoscopic Cholecystectomy, a Randomized Controlled Clinical Study

NCT05728463

Cholecystectomy, Laparoscopic

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This is a randomized controlled clinical trial that aims to collect a sample within two years from the date of approval of the Scientific Research Council at Damascus University.

The study will focus on a group of patients who will undergo a transperitoneal laparoscopic pyelolithotomy surgery.

The patients will be randomly divided into two groups. The first group will undergo a traditional transperitoneal laparoscopic pyelolithotomy, which involves application of anterior pyelotomy.

The second group will receive a modified transperitoneal laparoscopic pyelolithotomy, which involves application of posterior pyelotomy.

The data will be compared between the two groups in terms of the mean duration of surgery ,mean time for oral intake ,and mean hospital stay

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Large Renal Stone

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Anterior Pyelotomy

Traditional transperitoneal laparoscopic pyelolithotomy:

Patients who were randomized to receive classic transperitoneal laparoscopic pyelolithotomy

Group Type EXPERIMENTAL

traditional transperitoneal laparoscopic pyelolithotomy

Intervention Type PROCEDURE

Performing anterior Pyelotomy.

Posterior Pyelotomy

Modified transperitoneal laparoscopic pyelolithotomy:

Patients who were randomized to receive modified transperitoneal laparoscopic pyelolithotomy by applying posterior pyelotomy.

Group Type EXPERIMENTAL

modified transperitoneal laparoscopic pyelolithotomy

Intervention Type PROCEDURE

Performing posterior pyelotomy

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

traditional transperitoneal laparoscopic pyelolithotomy

Performing anterior Pyelotomy.

Intervention Type PROCEDURE

modified transperitoneal laparoscopic pyelolithotomy

Performing posterior pyelotomy

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

TLP

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients with large renal pelvic stone \> 2 cm .
* failure of minimally invasive approaches such as PCNL or ESWL
* stones that were neither amenable to ESWL nor were ideally suitable for PCNL
* Patient's preference for a quick one-stage procedure.
* Negative urine culture

Exclusion Criteria

* Patients refusing study participation.
* Contraindication to general anesthesia.
* Contraindication to laparoscopic surgery.
* Patients with an intrarenal pelvis.
* Previous surgical on the same kidney.
* Associated anatomical deformity.

Minimum Eligible Age

15 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No