Epidemiological Features of Emergent Highly Resistant Bacteria in Tunisian Intensive Care Units

NCT ID: NCT06392568

Last Updated: 2024-04-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-04-01

Study Completion Date

2024-05-31

Brief Summary

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Investigate the epidemiology, risk factors and impact on clinical practice of healthcare-associated infections with emergent highly drug-resistant (eHDR) pathogens, particularly carbapenem resistant enterobacteriaceae and glycopeptides-resistant enterococcus.

Detailed Description

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In 2022, a previous one-day point-prevalence multicenter study (NOSOREA2, NCT05547646) showed that most prevalent pathogens causing healthcare-associated infections were carbapenem resistant enterobacteriaceae. In 2017, (NOSOREA1, LA TUNISIE MEDICALE - 2018 ; Vol 96 (10/11)), most prevalent pathogens were non-fermenting pathogens.

Faced with this major epidemiological change within Tunisian ICUs, we decided to launch a 3rd survey under the aegis of the 'Association tunisienne de réanimation'. We aimed to investigate the epidemiology, risk factors and impact on clinical practice of healthcare-associated infections with emergent highly drug-resistant (eHDR) pathogens, particularly carbapenem resistant enterobacteriaceae and glycopeptides-resistant enterococcus. So we conducted a multicenter prospective collection that will take place over 2 months.

Conditions

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Cross Infection Carbapenem Resistant Bacterial Infection Vancomycin-Resistant Enterococcal Infection Critical Illness

Keywords

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Critical care Healthcare Associated Infections Drug resistance

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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eHDR+

Patients with Emergent Highly Resistant Bacteria healthcare associated infection

epidemiological records

Intervention Type OTHER

Healthcare associated infections due to emergent highly resistant bacteria, sites, risk factors, treatment and outcome

eHDR-

Patients without Emergent Highly Resistant Bacteria healthcare associated infection

No interventions assigned to this group

Interventions

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epidemiological records

Healthcare associated infections due to emergent highly resistant bacteria, sites, risk factors, treatment and outcome

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult ICU patients admitted during the study period

Exclusion Criteria

* none
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abderrahmane Mami Hospital

OTHER

Sponsor Role lead

Responsible Party

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Amira JAMOUSSI

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Amira JAMOUSSI, Professor

Role: PRINCIPAL_INVESTIGATOR

Abderrahmen Mami Hospital

Locations

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Abderrahmen Mami

Ariana, Tunis Governorate, Tunisia

Site Status RECRUITING

Countries

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Tunisia

Central Contacts

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Amira JAMOUSSI, Professor

Role: CONTACT

Phone: +21698375250

Email: [email protected]

Jalila BEN KHELIL, Professor

Role: CONTACT

Phone: +21653689799

Email: [email protected]

Facility Contacts

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JAMOUSSI Amira, Pr

Role: primary

Other Identifiers

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ATR

Identifier Type: -

Identifier Source: org_study_id