EQQUAL-NM for the Promotion of Smoking Cessation in Sexual and Gender Minority Young Adults in New Mexico

NCT ID: NCT06386432

Last Updated: 2025-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-01

Study Completion Date

2026-04-01

Brief Summary

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This clinical trial assesses the acceptability and efficacy of Empowered, Queer, Quitting, and Living--New Mexico (EQQUAL-NM), a smoking cessation intervention for sexual and gender minority young adults in New Mexico. Smoking prevalence among sexual and gender minority (SGM) adults in New Mexico is more than twice as high as non-SGM adults. Helping young adult tobacco users to quit is critical, yet there have been few efforts to develop tailored treatments specifically for this population. EQQUAL-NM is a digital smoking cessation intervention designed specifically for SGM young adult smokers in New Mexico and may help them quit smoking.

Detailed Description

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OUTLINE:

Participants are randomized to 1 of 2 groups.

GROUP I: Participants receive access to a self-guided, smartphone app-delivered quit smoking program, called EQQUAL-NM (Program A) that helps explore personal values and teaches participants about smoking triggers and skills to help them manage cravings and accept thoughts and feelings related to smoking. Participants receive text message reminders and prompts on study. Some participants also undergo collection of a saliva sample during follow-up.

GROUP II: Participants receive access to a self-guided, smartphone app-delivered quit smoking program, called EQQUAL-NM (Program B) that is based on current clinical practice guidelines for tobacco cessation to help them quit smoking. This program helps with quit advice, tracking progress on quitting smoking, and managing cravings. Participants receive text message reminders and prompts on study. Some participants also undergo collection of a saliva sample during follow-up.

After completion of study intervention, patients are followed up at 3 months.

Conditions

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Cigarette Smoking-Related Carcinoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors
Any outcome evaluator who has contact with participants will remain blinded to treatment group assignment until the final set of questions regarding acceptability of specific program components is asked.

Study Groups

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Arm I (EQQUAL-NM, Program A)

Participants receive self-guided smartphone app-delivered EQQUAL-NM (Program A) intervention on study. Participants also receive motivational messages, reminders and smoking cessation information via text messages. Some participants also complete at-home saliva sample collection during follow-up.

Group Type EXPERIMENTAL

Smartphone App-delivered Smoking Cessation Intervention

Intervention Type BEHAVIORAL

Receive access to EQQUAL-NM (Program A) intervention

Health Promotion and Education

Intervention Type OTHER

Receive text message reminders, motivational messages and prompts via SMS text messages (Program A)

Biospecimen Collection

Intervention Type OTHER

Complete at-home saliva sample collection

Questionnaire Administration

Intervention Type OTHER

Ancillary studies

Arm II (EQQUAL-NM, Program B)

Participants receive self-guided smartphone app-delivered EQQUAL-NM (Program B) intervention on study. Participants also receive motivational messages, reminders and smoking cessation information via text messages. Some participants also complete at-home saliva sample collection during follow-up.

Group Type ACTIVE_COMPARATOR

Smartphone App-delivered Smoking Cessation Intervention

Intervention Type BEHAVIORAL

Receive access to EQQUAL-NM (Program B) intervention

Health Promotion and Education

Intervention Type OTHER

Receive text message reminders, motivational messages and prompts via SMS text messages (Program B)

Biospecimen Collection

Intervention Type OTHER

Complete at-home saliva sample collection

Questionnaire Administration

Intervention Type OTHER

Ancillary studies

Interventions

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Smartphone App-delivered Smoking Cessation Intervention

Receive access to EQQUAL-NM (Program A) intervention

Intervention Type BEHAVIORAL

Smartphone App-delivered Smoking Cessation Intervention

Receive access to EQQUAL-NM (Program B) intervention

Intervention Type BEHAVIORAL

Health Promotion and Education

Receive text message reminders, motivational messages and prompts via SMS text messages (Program A)

Intervention Type OTHER

Health Promotion and Education

Receive text message reminders, motivational messages and prompts via SMS text messages (Program B)

Intervention Type OTHER

Biospecimen Collection

Complete at-home saliva sample collection

Intervention Type OTHER

Questionnaire Administration

Ancillary studies

Intervention Type OTHER

Other Intervention Names

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Smoking and Tobacco Use Cessation Intervention Smoking and Tobacco Use Cessation Intervention Text Message-Based Intervention Text Message-Based Intervention Saliva Sample Collection

Eligibility Criteria

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Inclusion Criteria

* Self-identify being between 18 and 30 years of age
* Self-identify as a sexual and/or gender minority (i.e., a sexual orientation other than straight and/or gender that doesn't match sex assigned at birth)
* Currently reside in New Mexico, with a New Mexico mailing address, and anticipate remaining in New Mexico for the duration of the study (3 months)
* Self-report smoking at least 1 cigarette per week in the 30 days prior to screening
* Own an Android phone or iPhone
* Have at least weekly internet access for the next three months
* Willing and able to stream audio and video for this study
* Current use of a personal email account
* Current use of text messaging
* Interested in participating in the study for themselves (versus \[vs\] someone else)
* Self-report that they have not participated in one of Fred Hutch's/NMSU's prior smoking cessation studies
* Understand and agree to the conditions of compensation
* Currently not incarcerated
* Participants must be willing to use the assigned intervention program, complete the study assessments, and agree to the online consent form in English

Exclusion Criteria

* Current use of other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (but initiating these treatments during the study is allowed)
* Member of the same household as another research participant
* Previous use of the National Cancer Institute (NCI) QuitGuide app
* Google voice number as sole phone number
* Does not pass study fraud prevention protocol
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

National Cancer Institute Center to Reduce Cancer Health Disparities

UNKNOWN

Sponsor Role collaborator

New Mexico State University

OTHER

Sponsor Role collaborator

Fred Hutchinson Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jaimee Heffner

Role: PRINCIPAL_INVESTIGATOR

Fred Hutch/University of Washington Cancer Consortium

Locations

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Fred Hutch/University of Washington Cancer Consortium

Seattle, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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NCI-2024-02453

Identifier Type: REGISTRY

Identifier Source: secondary_id

FHIRB0020404

Identifier Type: OTHER

Identifier Source: secondary_id

U54CA132381

Identifier Type: NIH

Identifier Source: secondary_id

View Link

RG1124189

Identifier Type: -

Identifier Source: org_study_id

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