Cervical/Thoracic Neuromodulation and Nociceptive Processing

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-19

Study Completion Date

2024-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Several studies have demonstrated that direct currents delivered through the skin at the level of the low-thoracic spinal cord can influence spinal cord function. In human volunteers, anodal low-thoracic transcutaneous spinal direct current stimulation (tsDCS) alters spinal processing of nociceptive inputs. Whether cervical tsDCS is able to do the same is less well known. In this double-blinded, sham-controlled and cross-over trial, the investigators will compare the effects on the nociceptive processing of healthy volunteers of cervical and low-thoracic tsDCS.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Effects of tDAS Combined With Stabilization Exercises in Individuals With Chronic Neck Pain

NCT06193564

Neck Pain

COMPLETED NA

Treatment of Neck Pain With Transcranial Direct Current Stimulation

NCT04729270

Cervical Syndrome

COMPLETED NA

Cerebellar Transcranial Direct Current Stimulation (tDCS) in Patients With Isolated Cervical Dystonia (CD)

NCT07014384

Isolated Cervical Dystonia

RECRUITING NA

TDCS* and Laterality Trainnning in Patients With Chronic Neck Pain

NCT06204627

Neck Pain Chronic Pain

RECRUITING NA

The Effect of a Single Spinal Manipulation on Cardiovascular Autonomic Activity

NCT03273868

Manipulation, Spinal

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The investigators will compare the effects on the nociceptive processing of healthy volunteers of cervical and low-thoracic tsDCS. This study will be a double-blinded, sham-controlled, cross-over trial. Each participant will undergo three experimental sessions (anodal cervical tsDCS and sham thoracic tsDCS vs. sham cervical tsDCS and anodal thoracic tsDCS vs. sham cervical tsDCS and sham thoracic tsDCS), separated by at least one week.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Nociceptive Pain

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Anodal cervical tsDCS

Participants will receive:

1. 20 minutes of 2.5 milliamperes (mA) anodal tsDCS at the cervical level.
2. 20 minutes of sham tsDCS at the low-thoracic level.

Group Type EXPERIMENTAL

cervical a-tsDCS

Intervention Type DEVICE

Anodal transcutaneous spinal direct current stimulation (a-tsDCS)

Anodal thoracic tsDCS

Participants will receive:

1. 20 minutes of sham tsDCS at the cervical level.
2. 20 minutes of 2.5 milliamperes (mA) anodal tsDCS at the low-thoracic level.

Group Type EXPERIMENTAL

thoracic a-tsDCS

Intervention Type DEVICE

Anodal transcutaneous spinal direct current stimulation (a-tsDCS)

Sham tsDCS

Participants will receive:

1. 20 minutes of sham tsDCS at the cervical level.
2. 20 minutes of sham tsDCS at the low-thoracic level.

Group Type SHAM_COMPARATOR

sham tsDCS

Intervention Type DEVICE

Sham transcutaneous spinal direct current stimulation (s-tsDCS)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

cervical a-tsDCS

Anodal transcutaneous spinal direct current stimulation (a-tsDCS)

Intervention Type DEVICE

thoracic a-tsDCS

Anodal transcutaneous spinal direct current stimulation (a-tsDCS)

Intervention Type DEVICE

sham tsDCS

Sham transcutaneous spinal direct current stimulation (s-tsDCS)

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Healthy young adults

Exclusion Criteria

* Known medical conditions (e.g., diabetes, neuropathy, psychiatric disorders, seizure, migraine, pacemaker or other implanted medical devices...)
* Use of any medication (except contraception)

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes