Validation of a Novel Sham Cervical Spinal Manipulation Procedure

NCT ID: NCT00978094

Last Updated: 2010-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-02-28

Study Completion Date

2010-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Primary hypotheses:

Ho1: In chronic neck pain patients, randomly treated with either a "sham" or "real" cervical manipulation procedure, the probability of perceiving a Real Manipulation Procedure is equal to the probability of obtaining a Real Manipulation Procedure, AND, Ho2: Spinal tenderness will remain unchanged following the treatment procedure for both groups.

Secondary (null) hypotheses:

1. Neck pain, cervical ranges of motion and paraspinal EMG responses to pressure pain will remain unchanged in both groups;
2. there will be no differences between groups with respect to 2a) neck joint cavitations and 2b) forces across the cervical spine measured during the manoeuvres.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

1. Develop a randomized controlled clinical trial design to optimize the testing of the effects of a sham vs real cervical manipulation.
2. Use novel modifications of both a sham a real manipulation to create "procedures" designed to optimize group equivalence in the RCT design. Then, evaluate the accuracy of 'patient post-treatment perception of treatment type' versus actual administered treatment (primary outcome #1).
3. Quantitatively evaluate group differences in local soft-tissue tenderness by algometry (primary outcome #2), as well as changes in self-reported neck pain, ranges of motion, myoelectric responses in selected neck muscles and forces imparted during the procedures.
4. Evaluate the occurrence of neck joint cavitation during the manoeuvres comprising these procedures.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Chronic Neck Pain

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 21-55 years old with chronic neck pain, Males/Females
* Between 30-60 NRS 101 Scale
* ≥ 4 weeks mechanical neck pain

Exclusion Criteria

* Cervical Spine Surgery
* Medically uncontrolled High Blood Pressure
* Past History of Stroke
* Upper Respiratory Infection within 4 weeks
* Current Symptoms of Dizziness
* Tinnitus, Blurred Vision, Vertigo, Sensory Motor Disturbance
* Current use of anticoagulant therapy
* Connective Tissue Disorder
* Primary Fibromyalgia or myofascial pain
* Metabolic/Neoplastic Bone Disease
Minimum Eligible Age

21 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Canadian Memorial Chiropractic College

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Canadian Memorial Chiropractic College

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Howard Vernon, BA, DC, PhD, FCCS, FCCRS

Role: PRINCIPAL_INVESTIGATOR

CMCC

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Canadian Memorial Chiropractic College

Toronto, Ontario, Canada

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Canada

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

1R21AT004396-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

072155

Identifier Type: -

Identifier Source: org_study_id