Fertility-sparing in Early-stage Cervcial Cancer: The ETERNITY Project

NCT ID: NCT06351228

Last Updated: 2024-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-30

Study Completion Date

2024-12-31

Brief Summary

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The ETERNITY project is a retrospective analysis of outcomes of patients undergoing fertility-sparing treatment for cervcial cancer.

The primary aim is to report outcomes of those patients.

Other aims included:

1. Evaluation about the effectiveness of different treatment modalities;
2. Evaluation of outcomes according to different stages of disease;
3. Evaluation of the impactof neoadjuvant chemotherapy in patients undergoing conservative surgery

Detailed Description

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Conditions

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Cervical Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Conization plus nodal evaluation

Conization plus nodal evaluation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Histological confirmed cervical cancer
* FIGO Stage IA1-IB3
* Fertility-sparing (conization plus nodal dissection)

Exclusion Criteria

* age less than 18 yrs
* age more than 50 yrs
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Fondazione IRCCS Istituto Nazionale dei Tumori di Milano

Milan, Lombardy, Italy

Site Status

Countries

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Italy

References

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Bogani G, Scambia G, Malzoni M, Casarin J, Vizzielli G, Amant F, Raspagliesi F; Investigators of the ETERNITY Project. Chemo-conization in Early-sTage cERvical caNcer >2 cm scheduled for fertilItY-sparing approach: an analysis of the ETERNITY project. Int J Gynecol Cancer. 2025 Apr;35(4):101643. doi: 10.1016/j.ijgc.2025.101643. Epub 2025 Jan 17.

Reference Type DERIVED
PMID: 39955179 (View on PubMed)

Other Identifiers

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5720

Identifier Type: -

Identifier Source: org_study_id

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