Risk Factors for AKI in Patients Undergoing VATS for Pulmonary Resection
NCT ID: NCT06341933
Last Updated: 2025-01-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
100 participants
OBSERVATIONAL
2024-04-15
2025-12-15
Brief Summary
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The research will be conducted at SBÜ Ankara Atatürk Sanatorium Training and Research Hospital. The study will involve patients who have given informed consent and will undergo VATS with standard anaesthesia monitoring. Anaesthesia management will follow our routine protocol in our clinic.
Patients will be divided into two groups based on whether they have a more than 25% decrease in estimated glomerular filtration rate (t-GFH) and/or a 1.5-fold increase in serum creatinine and/or a 6-hour urine volume of less than 0.5 ml/kg/h. The patients will be divided into two groups based on this definition, and the risk factors between these groups will be analysed.
The preoperative routine blood values, demographic data (age, gender, height, weight, and BMI), ASA physical status, smoking and alcohol habits, comorbidities, and regular medication use will be recorded. Intraoperative urine output and haemodynamic parameters will also be monitored. Routine blood gas analysis, blood urea nitrogen (BUN), glomerular filtration rate (GFR), albumin, haemoglobin, sodium, potassium, chlorine, and magnesium will be measured and recorded, along with urine output and t-GFH. Patients will be evaluated in the hospital on the day the surgeon calls for a postoperative check-up and on the 30th postoperative day to see if there are any complications.
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Detailed Description
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Conditions
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Study Design
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OTHER
PROSPECTIVE
Study Groups
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Acute Kidney Injury (NO)
In the postoperative period, patients with normal renal function.
Duration of Surgery
Total surgery time in minutes
Volume of Fluid in Surgery
Fluid volume given during surgery in ml
Blood Loss
Blood loss during surgery in ml
Acute Kidney Injury (YES)
There has been a decrease of more than 25% in the estimated glomerular filtration rate (t-GFH), and/or a 1.5-fold increase in serum creatinine, and/or a 6-hour urine volume of less than 0.5 ml/kg/h.
Duration of Surgery
Total surgery time in minutes
Volume of Fluid in Surgery
Fluid volume given during surgery in ml
Blood Loss
Blood loss during surgery in ml
Interventions
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Duration of Surgery
Total surgery time in minutes
Volume of Fluid in Surgery
Fluid volume given during surgery in ml
Blood Loss
Blood loss during surgery in ml
Eligibility Criteria
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Inclusion Criteria
* American Society of Anesthesiologists (ASA) physical status 1-3,
* Data of patients who will undergo wedge resection, segmentectomy or lobectomy with elective VATS due to lung malignancy will be examined prospectively.
Exclusion Criteria
* Those with impaired renal function (the upper limit of the creatinine reference range is more than 50%; 1.3 mg/dL for men and 1.1 mg/dL for women),
* A radiological examination was performed using radiocontrast material in the preoperative period,
* Clinically and radiologically diagnosed with congestive heart failure and treatment has been started,
* Having a history of pulmonary edema,
* Those who have used steroids and non-steroidal anti-inflammatory drugs for a long time (exceeding 30 days),
* Intubated to intensive care unit,
* In need of massive peroperative blood transfusion,
* Patients with deficiencies in the parameters examined will be excluded from the study.
18 Years
65 Years
ALL
No
Sponsors
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Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
OTHER
Responsible Party
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Ali Alagoz
Department of anesthesiology and reanimation, Principal Investigator, Specialist Doctor
Principal Investigators
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Ali ALAGÖZ, professor
Role: PRINCIPAL_INVESTIGATOR
Ankara Ataturk Sanatorium Training and Research Hospital
Locations
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Ankara Atatürk Sanatorium Training and Research Hospital
Ankara, Keçiören, Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2024-BÇEK/41
Identifier Type: -
Identifier Source: org_study_id
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