Calcified Cerebral Embolism: a Descriptive Study in a Large Single Center Cohort

NCT ID: NCT06309069

Last Updated: 2026-01-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

79 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-04-16

Study Completion Date

2024-11-30

Brief Summary

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Calcified cerebral embolism (CCE) is a relatively rare but underdiagnosed cause of infarction. CCE diagnosis is made by CT. Radiological characteristics of CCE have been reported in small case series. The aim of this study was to describe clinical and radiological characteristics of CCE in a large number of patients, and to compare patients with different radiological CCE characteristics.

Detailed Description

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Conditions

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Calcified Cerebral Embolism

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients with CCE

CCE patients identified between 2015 and 2023

None, purely observational study

Intervention Type OTHER

None, purely observational study

Interventions

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None, purely observational study

None, purely observational study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with CEE treated with intravenous thrombolysis (IVT) between 2015 and 2020 managed at the CHU de Nîmes or Patients with TIA/stroke with ECC identified on CT between 12/2019 and 04/2023 managed at CHU de Nîmes

Exclusion Criteria

* Patient's refusal to use his/her data
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Universitaire de Nīmes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anissa MEGZARI

Role: STUDY_DIRECTOR

Centre Hospitalier Universitaire de Nīmes

Locations

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CHU de Nîmes

Nîmes, , France

Site Status

Countries

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France

References

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Serghine Y, Laurent-Chabalier S, Thouvenot E, Parvu T, Renard D. Clinical and radiological characteristics of calcified cerebral embolism: a large case series including 242 calcified cerebral embolism. Acta Neurol Belg. 2025 Apr;125(2):463-468. doi: 10.1007/s13760-025-02719-w. Epub 2025 Jan 15.

Reference Type RESULT
PMID: 39813005 (View on PubMed)

Other Identifiers

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IRB 24.01.01

Identifier Type: OTHER

Identifier Source: secondary_id

LOCAL/2024/TP-01

Identifier Type: -

Identifier Source: org_study_id

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