Longitudinal Changes in Achilles Tendon and Medial Gastrocnemius Muscle Architecture During a 156-km Ultradistance Trail Running Event

NCT ID: NCT06297317

Last Updated: 2025-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

55 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-11

Study Completion Date

2024-02-01

Brief Summary

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This study aimed to assess the longitudinal changes in triceps surae muscle-tendon architecture to an ultra distance trail running. Experienced trail runners (N=55, 78% men, age: 45.2 \[13.5\] years) participated in a 156-km trail run (6000m climbing) consisting in six 26-km laps. The resting architectural properties of triceps surae muscle-tendon were measured using ultrasound imaging for Achille tendon cross-sectional area (AT CSA), medial gastrocnemius muscle pennation angle, thickness, length and fiber length. Measurements were performed the day before the race (Baseline), at 52-km (T1), at 104-km (T2), at 156-km (T3) and 12 hours after the race (H12).

Detailed Description

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Conditions

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Achilles Tendinopathy Calf Injury Sport Injury Lower Limb Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Experienced long-distance trail runners

All the participants of the First 'Trail Scientifique de Clécy 2021". This was a multidisciplinary protocol to investigate the mechanisms that contribute to performance during an ultradistance trail race (156-km)

Ultrasound measurement of triceps surae muscle-tendon architecture

Intervention Type DIAGNOSTIC_TEST

The resting plantar-flexors MTU architecture assessment was performed using a conventional B-mode and extended-field-of-view (EFOV) ultrasound imaging. Achille tendon cross-sectionnal area, Medial gastrocnemius thickness, pennation angle, fascicle length and muscle length were collected on the dominant lower limb.

Interventions

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Ultrasound measurement of triceps surae muscle-tendon architecture

The resting plantar-flexors MTU architecture assessment was performed using a conventional B-mode and extended-field-of-view (EFOV) ultrasound imaging. Achille tendon cross-sectionnal area, Medial gastrocnemius thickness, pennation angle, fascicle length and muscle length were collected on the dominant lower limb.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Experienced runners voluntarily participating in the Trail Scientifique de Clécy (156 km/6000 D+)
* Participants who had already completed 2 ultratrail races (+160 km and -160 km), at least one of them in the past 24 months; the participants had to justify their events and rankings
* Participants affiliated with a social security system or those who were a beneficiary of such a system
* Participants who could speak and read the French language
* Participants with the ability to physically participate in the ultraendurance race
* Participants with the ability to provide written consent for participation in the study

Exclusion Criteria

* Participants with cardiac or extracardiac contraindications to intense physical activity
* Participants who had run a mountain ultramarathon (160 km) after September 2, 2021
* Pregnant or breastfeeding women
* Minor participants
* Participants included in another biomedical research protocol during this study
* Participants with recent muscular and orthopedic injuries, limiting running for \<15 days
* Participants with a history of ankle joint surgery (eg, arthrodesis)
* Participants with a history of foot or ankle surgery
* Participants with lower-limb pathology or trauma
Minimum Eligible Age

25 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Caen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Caen Normandie

Caen, , France

Site Status

Countries

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France

References

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Mauvieux B, Hingrand C, Drigny J, Hodzic A, Baron P, Hurdiel R, Jouffroy R, Vauthier JC, Pessiglione M, Wiehler A, Degache F, Pavailler S, Heyman E, Plard M, Noirez P, Dubois B, Esculier JF, Nguyen AP, Van Cant J, Roy Baillargeon O, Pairot de Fontenay B, Delaunay PL, Besnard S. Study of the Kinetics of the Determinants of Performance During a Mountain Ultramarathon: Multidisciplinary Protocol of the First Trail Scientifique de Clecy 2021. JMIR Res Protoc. 2022 Jun 15;11(6):e38027. doi: 10.2196/38027.

Reference Type BACKGROUND
PMID: 35704381 (View on PubMed)

Other Identifiers

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Trailstiff

Identifier Type: -

Identifier Source: org_study_id

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