Xanthohumol and Viral Infections (XL)

NCT ID: NCT06286657

Last Updated: 2025-04-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-08-01

Study Completion Date

2025-12-30

Brief Summary

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The aim of the present study is to determine if a regular oral supplementation of xanthohumol attenuate the severity of symptoms and duration of´viral infections.

Detailed Description

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In this placebo-controlled study, blood is taken on the first day of the study, followed by a 90-day intervention with xanthohumol or a placebo, which is taken twice daily. Blood samples will be taken on day 0, day 45 and day 90. Should the study participants develop a respiratory infection during the study, they will be asked to perform a self-test.

Conditions

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Infection Viral

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Intervention

Participants consume twice per day a study drink which contains 0,75 mg soluble Xanthohumol for 90 days

Group Type EXPERIMENTAL

Xanthohumol

Intervention Type DIETARY_SUPPLEMENT

Participants consume twice per day a study drink which contains 0,75 mg soluble Xanthohumol for 90 days

Placebo

Participants consume twice per day a study drink which contains 0 mg soluble Xanthohumol for 90 days

Group Type EXPERIMENTAL

Placebo

Intervention Type DIETARY_SUPPLEMENT

Participants consume twice per day a study drink which contains 0 mg soluble Xanthohumol for 90 days

Interventions

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Xanthohumol

Participants consume twice per day a study drink which contains 0,75 mg soluble Xanthohumol for 90 days

Intervention Type DIETARY_SUPPLEMENT

Placebo

Participants consume twice per day a study drink which contains 0 mg soluble Xanthohumol for 90 days

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* healthy
* BMI \>18 kg/m² or \< 28kg/m²

Exclusion Criteria

* food intolerances
* food allergies
* chronic inflammatory diseases
* metabolic diseases
* viral or bacterial infections within the last 3 weeks of inclusion
* intake of immunosuppressive medication
* severe acute respiratory syndrome coronavirus type 2-infection in the last 4 months
* influenza infection in the "current" flu season
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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Prof. Dr. Ina Bergheim

Prof. Dr. Ina Bergheim

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Vienna

Vienna, , Austria

Site Status RECRUITING

Countries

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Austria

Central Contacts

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Ina Bergheim, Prof. Dr.

Role: CONTACT

+43-1-4277-54981

Facility Contacts

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Ina Bergheim, Prof. Dr.

Role: primary

+43-1-4277-54981

Other Identifiers

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UVienna23a

Identifier Type: -

Identifier Source: org_study_id

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