FeelFit: High-intensity Interval Training to Improve Self-reported Physical Fitness in Brain Tumor Patients

NCT ID: NCT06282562

Last Updated: 2025-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-01

Study Completion Date

2026-08-15

Brief Summary

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The FeelFit study aims to assess the effectiveness of High-Intensity Interval Training (HIIT) in improving self-reported physical fitness in adult brain tumor patients during periods of stable disease, as compared to a waiting-list control group. Furthermore, several secondary and exploratory outcomes will be evaluated. The study is part of the GRIP (GuaRding quality survivorshiP) project, which aims to improve quality of life in brain tumor patients.

Detailed Description

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Conditions

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Brain Tumor, Primary Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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HIIT

The intervention group will perform High-Intensity Interval Training (HIIT), consisting of two supervised exercise sessions per week on a stationary bike, for 12 weeks.

In addition, participants will receive information on general guidelines for weekly physical activity levels and will be asked to keep an exercise diary.

Group Type EXPERIMENTAL

High-Intensity Interval Training (HIIT)

Intervention Type OTHER

Individualized High-Intensity Interval Training (HIIT) program with two exercise sessions per week for 12 weeks. The exercise sessions will be conducted on a stationary bike, with intensity tailored to each participant's maximum exercise capacity.

Waiting-list

The control group on the waiting list will be given the option to perform High-Intensity Interval Training (HIIT) after their participation in the study.

In addition, also participants from the waiting-list control group will receive information on general guidelines for weekly physical activity levels and will be asked to keep an exercise diary.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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High-Intensity Interval Training (HIIT)

Individualized High-Intensity Interval Training (HIIT) program with two exercise sessions per week for 12 weeks. The exercise sessions will be conducted on a stationary bike, with intensity tailored to each participant's maximum exercise capacity.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* reduced self-reported physical fitness;
* minimum age of 18 years;
* diagnosed with a primary brain tumor;
* stable disease, i.e. no signs of radiological or clinical tumor progression;
* no oncological treatment for at least two months prior to inclusion;
* able to speak, read and write in Dutch.

Exclusion Criteria

* Karnofsky Performance Score \< 70;
* already participated in a HIIT program \< 1 month prior;
* contraindication of exercise.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Amsterdam UMC, location VUmc

OTHER

Sponsor Role lead

Responsible Party

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Linda Douw

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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VU University Medical Centers, location VUmc

Amsterdam, , Netherlands

Site Status RECRUITING

Countries

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Netherlands

Central Contacts

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Marieke Blom, Msc

Role: CONTACT

+31 6 21522442

Facility Contacts

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Marieke Blom, Msc

Role: primary

+31621522442

Other Identifiers

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NL84223.018.23

Identifier Type: -

Identifier Source: org_study_id

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