A Study on the Relationship Between Gastric Xanthoma and Gastric Cancer and Precancerous Lesions

NCT ID: NCT06282484

Last Updated: 2024-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1260 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2023-09-29

Brief Summary

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To explore the effects of gastric xanthoma on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.

Detailed Description

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This is a large-scale single center case-control study. Patients were consecutively enrolled and divided into gastric cancer group, gastric precancerous lesions group, and chronic gastritis group, according to histopathological results.Record the location and quantity of gastric xanthoma and situation of Helicobacter pylori infection in each patient.

Conditions

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Gastric Xanthoma Helicobacter Pylori Infection Gastric Cancer Intestinal Metaplasia Precancerous Lesions

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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chronic gastritis

patients with chronic non-atrophic gastritis and chronic atrophic gastritis according to histopathological results

No interventions assigned to this group

precancerous lesion

patients with gastric intestinal metaplasia and intraepithelial neoplasia according to histopathological results

No interventions assigned to this group

gastric cancer

patients with gastric cancer according to histopathological results

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Age range from 18 to 75 years old, regardless of gender;
2. Endoscopic/pathological diagnosis: chronic non atrophic gastritis/chronic atrophic gastritis/intestinal metaplasia/dysplasia Hyperplasia/gastric cancer
3. Voluntarily sign an informed consent form.

Exclusion Criteria

1. Previously underwent upper gastrointestinal surgery
2. Previous diagnosis of malignant tumors
3. Individuals who are unable to cooperate with the questionnaire survey due to mental disorders or other reasons
4. Those who cannot be observed by endoscopy due to acute upper gastrointestinal bleeding or other reasons
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Xijing Hospital of Digestive Diseases

OTHER

Sponsor Role lead

Responsible Party

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Yongquan Shi

Principal Investigator, Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yongquan Shi, PhD

Role: STUDY_DIRECTOR

Xijing Hosipital of Digestive Disease

Locations

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Xijing Hosipital of Digestive Disease

Xi'an, Shaanxi, China

Site Status

Countries

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China

Other Identifiers

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KY20232348-C-1

Identifier Type: -

Identifier Source: org_study_id

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