Associations Among Serum and Gastric Juice Bile Acid Profile, Bile Acid-microbiota Cross-talk in Stomach and the Development of Gastric Cancer
NCT ID: NCT04660058
Last Updated: 2023-01-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
73 participants
OBSERVATIONAL
2020-12-20
2022-01-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
OTHER
Study Groups
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chronic gastritis
patients with chronic non-atrophic gastritis and chronic atrophic gastritis according to histopathological results
No interventions assigned to this group
precancerous lesion
patients with gastric intestinal metaplasia and intraepithelial neoplasia according to histopathological results
No interventions assigned to this group
gastric cancer
patients with gastric cancer according to histopathological results
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
2. No history of antibiotic or probiotic use for 8 weeks;
3. No preoperative chemotherapy or radiation therapy prior to the examination;
4. Voluntary intravenous blood collection, gastroscopy, extraction of gastric juice and pathological biopsy.
5. Voluntary testing for H. pylori
Exclusion Criteria
2. Previous diagnosis of Malignant Tumors;
3. Presence of a disease or medication that affects bile acid metabolism, such as endocrine or autoimmune diseases;
4. Recent use of drugs that affect gastrointestinal motility;
5. Presence of contraindications to endoscopy;
6. pregnant and lactating women;
7. Those with mental disorders;
8. Refusal to sign the informed consent form.
18 Years
75 Years
ALL
No
Sponsors
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Xijing Hospital of Digestive Diseases
OTHER
Responsible Party
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Yongquan Shi
Principal Investigator, Clinical Professor
Locations
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Xijing Hosipital of Digestive Disease
Xi'an, Shaanxi, China
Countries
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Other Identifiers
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KY20202100-F-1
Identifier Type: -
Identifier Source: org_study_id
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