Vascular Affection in Behcet Disease

NCT ID: NCT06280430

Last Updated: 2024-02-28

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 90 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-03-01
• Study Completion Date: 2025-04-01

Brief Summary

To measure the level of serum elafin in patients with behcet disease and to assess the correlation between serum elafin and vascular affection and their relation with disease activity

Detailed Description

Behcet disease is a chronic multi systemic inflammatory disease characterized by recurrent oral and genital ulcers and multiple systemic affection . Elafin is a serine protease inhibitor produced mainly by epithelial cells . previous studies documented the role of serum elafin in pathogenesis of behcet disease.vascular complications may be one if the earliest manifestation leading to the diagnosis of behcet disease.

Conditions

Behcet Disease and Vascular Involvement

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: RETROSPECTIVE

Study Groups

Patients with behcet disease

No interventions assigned to this group

Healthy control group

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• patients diagnosed as behcet disease Age (20-45)

Exclusion Criteria

• age <20 and >45 Other autoimmune diseases Risk factors (ischemic heart disease, diabetes) Chronic conditions (malignancy, chronic kidney disease)

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 45 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Lobna Amer Araby Ahmed

Assuit

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

Vascular affection in behcet

Identifier Type: -

Identifier Source: org_study_id