Assessment of Endocan Serum Levels in Patients With Behcet Disease

NCT ID: NCT03853135

Last Updated: 2020-01-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

84 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-02-27

Study Completion Date

2019-12-16

Brief Summary

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The aim of our study was to assess serum endocan levels in patients with Behcet disease and to correlate it with various disease clinical and laboratory parameters of disease activity as well as carotid intima media thickness.

Detailed Description

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This study will be carried out on two groups:

• Group (I): Forty two patients diagnosed to have Behcets disease fulfilling the International Criteria for BD .

Group (II): including 42 age and sex matching healthy volunteers as control group.

(A) Clinical evaluation

1. Complete history taking.
2. Thorough clinical examination including opthalmologic evaluation .
3. Disease activity using The Behcet's disease current activity form (BD-DAF) . (B) Laboratory assessment:

All patients will be subjected to the following measurements:

1. ESR
2. CRP
3. CBC
4. liver and kidney function tests

d) Serum Endocan level e)triglycrides f) cholestrol C) carotid intima media thickness

Conditions

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Behçet

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Behçet group

Forty two patients diagnosed to have Behçet disease fulfilling the International Study Group Criteria for Behçet disease in whom measurement of serum endocan levels will be performed.

measurement of serum endocan

Intervention Type DIAGNOSTIC_TEST

measurement of serum levels of endocan

control group

including 42 age and sex matching healthy volunteers as control group in whom measurement of serum endocan levels will be performed.

measurement of serum endocan

Intervention Type DIAGNOSTIC_TEST

measurement of serum levels of endocan

Interventions

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measurement of serum endocan

measurement of serum levels of endocan

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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endothelial cell-specific molecule 1

Eligibility Criteria

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Inclusion Criteria

* patients with Behcets disease fulfilling the International Criteria for BD .

Exclusion Criteria

* infection
* malignancy
* other connective tissue disease
* chronic liver disease
* chronic kidney disease
* Diabetes mellitus
* hypertension
* hyperlipidemia
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Benha University

OTHER

Sponsor Role lead

Responsible Party

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Waleed Ahmed Salaheldeen Hassan

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Waleed Hassan, MD

Role: PRINCIPAL_INVESTIGATOR

Benha university- Qaluibya- Egypt

Locations

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Benha University Hospital

Banhā, Qalyubia Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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BenhaU22019

Identifier Type: -

Identifier Source: org_study_id

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