Comparison of the Effect of Warfarin and Direct Oral Anticoagulants

NCT ID: NCT06269302

Last Updated: 2024-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

346 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-01

Study Completion Date

2022-12-31

Brief Summary

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In this study, it was aimed to compare the frequency of new oral anticoagulants and warfarin usage, and to reveal the rates of recurrent upper gastrointestinal bleeding among patients who applied to our hospital with upper gastrointestinal bleeding

Detailed Description

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The data of all patients who applied to Samsun Training and Research Hospital Internal Medicine with a diagnosis of upper gastrointestinal bleeding and hospitalized by Internal Medicine and Gastroenterology clinics or who underwent outpatient endoscopy between 01.01.2021 and 31.12.2021 were included. The patients' data were analyzed from the patient files and hospital automation system retrospectively. Patients who had recurrent upper GI bleeding were detected by controlling them over the hospital software system and by reaching each patient again. The frequency of the new generation oral anticoagulants usage in patients with re-bleeding was determined, and data such as re-bleeding rate, length of hospital stay, need for transfusion, and mortality were analyzed in the groups who did not use this drug and those who used it. The patient demographics were also compared between the groups who were using the new generation oral anticoagulants, acetylsalicylic acid or warfarin.

Conditions

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Anticoagulants and Bleeding Disorders Gastrointestinal Hemorrhage

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients with recurrent gastrointestinal bleeding

The data of all patients who applied to Samsun Training and Research Hospital for 12 months in 2022 and diagnosis of upper gastrointestinal bleeding and hospitalized by Internal Medicine and Gastroenterology clinics or who underwent outpatient endoscopy were included in the study.Patients who had recurrent upper GI bleeding were detected by controlling them over the hospital software system and by reaching each patient again. The frequency of use of new generation oral anticoagulants in patients with rebleeding was determined, and data such as rebleeding rate, length of hospital stay, need for transfusion, and mortality were analyzed in the groups who did not use this drug and those who used it.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age \>18 years old
* Upper gastrointestinal bleeding
* 12 months follow-up

Exclusion Criteria

* Age \<18 years old
* Lower gastrointestinal bleeding
* Esophageal variceal bleeding
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Samsun Education and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Duriye Sila Karagoz Ozen

MD, Internal Medicine Specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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DÜRİYE SILA KARAGÖZ ÖZEN, MD

Role: PRINCIPAL_INVESTIGATOR

Samsun Education and Research Hospital

Locations

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Samsun Education and Research Hospital

Samsun, İlkadım, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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2

Identifier Type: -

Identifier Source: org_study_id

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