Study of the Dynamics of Verbal and Non-verbal Interaction in Healthy Subjects, Through the Recording of Body Movements and Non-invasive Neurophysiological Techniques

NCT ID: NCT06251479

Last Updated: 2024-02-09

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 200 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-08-16
• Study Completion Date: 2026-08-16

Brief Summary

Based on study literature, the investigators can say that our study aims to give an explanation not only from a behavioral point of view but also with respect to what are the neuronal mechanisms underlying our ability to perceive and analyze our own and others' actions. This is essential to fully understand the complexity of our social behaviors. The knowledge of these mechanisms has a high value and relevant implications for many research fields both within and outside the neurosciences. The project aims to study the neurobehavioral correlates of verbal and non-verbal communication. Through the use of non-invasive behavioral and neurophysiological techniques, the study intends to highlight the neurobehavioral markers that allow to quantify the temporal evolution of communication dynamics in healthy subjects.

Detailed Description

Based on study literature, the investigators can say that our study aims to give an explanation not only from a behavioral point of view but also with respect to what are the neuronal mechanisms underlying our ability to perceive and analyze our own and others' actions. This is essential to fully understand the complexity of our social behaviors. The knowledge of these mechanisms has a high value and relevant implications for many research fields both within and outside the neurosciences. The project aims to study the neurobehavioral correlates of verbal and non-verbal communication. Through the use of non-invasive behavioral and neurophysiological techniques, the study intends to highlight the neurobehavioral markers that allow to quantify the temporal evolution of communication dynamics in healthy subjects.

1. the investigators intend to verify whether individual differences in the ability to discriminate the verbal and non-verbal signals of others are reflected in significant differences in the way the same actions are performed.

2. the investigators intend to quantify the behavioral variables during the execution of the action and observe how these are modified in the passage from a single execution to an interaction context.

3. the investigators intend to study how the interactive context influences the cerebral and cortico-muscular oscillatory dynamics during the preparation of the action.

4. the investigators intend to verify whether the activity of the motor system contributes not only to the execution of the action but also, if and, if so, to the perception of the actions of others

Conditions

Neuroscience; Neuromodulation

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SCREENING
• Blinding Strategy: SINGLE

Study Groups

A group behavioral 1

The first group will perform perceptual and verbal and non-verbal motor execution tasks, while behavioral measurement techniques will be used.

Group Type: EXPERIMENTAL

behavioral 1

Intervention Type: BEHAVIORAL

verbal and non verbal tasks

B group behavioral 2

The second group will perform the same tasks as group A and will be subjected to the same measurements as group A. Differently from group A, the members of group B will perform the experimental tasks together with another participant.

Group Type: EXPERIMENTAL

behavioral 2

Intervention Type: BEHAVIORAL

verbal and non verbal tasks with other partecipants

C group neuromoulation 1

The third group is identical to group A except that neurophysiological measurement techniques will also be applied.

Group Type: EXPERIMENTAL

neuromodulation 1

Intervention Type: DEVICE

registration with neurophysiological tecniques during verbal and non verbal tasks

D group neuromodulation 2

The fourth group is identical to group B except that neurophysiological measurement techniques will also be applied.

Group Type: EXPERIMENTAL

neuromodulation 2

Intervention Type: DEVICE

registration with neurophysiological tecniques during verbal and non verbal tasks with other partecipants

Interventions

behavioral 1

verbal and non verbal tasks

Intervention Type: BEHAVIORAL

behavioral 2

verbal and non verbal tasks with other partecipants

Intervention Type: BEHAVIORAL

neuromodulation 1

registration with neurophysiological tecniques during verbal and non verbal tasks

Intervention Type: DEVICE

neuromodulation 2

registration with neurophysiological tecniques during verbal and non verbal tasks with other partecipants

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Age range between 18 and 55 years
• written informed consent
• healthy subjects

Exclusion Criteria

• epilepsy or at risk of epileptic seizures,
• cardiac pacemaker wearers,
• presence of an implanted infusion pump,
• metal plaques in the skull or metal objects in the eye and skull taking neuroleptic drugs or tricyclic antidepressants,
• migraine or at risk of developing this disease.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

IRCCS Centro Neurolesi Bonino Pulejo

OTHER

Sponsor Role: lead

Responsible Party

Caterina Formica

Caterina Formica, PhD, PSY

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

IRCCS Centro Neurolesi Bonino Pulejo

Messina, , Italy

Site Status: RECRUITING

Countries

Italy

Facility Contacts

Caterina Formica, PhD, PSY

Role: primary

katia.formica@irccsme.it

+3909060128185

Other Identifiers

OMNIBUS2023

Identifier Type: -

Identifier Source: org_study_id