Analysis of Ocular Complications of AIDS Patients in Ophthalmic Consultation
NCT ID: NCT06250881
Last Updated: 2024-02-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
500 participants
OBSERVATIONAL
2023-10-01
2024-03-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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without ocular complication
The normal group was compared with the pathological group
No interventions assigned to this group
fundus opportunistic infections
AIDS patients are prone to opportunistic fundus infection, which show a characteristic changes in fundus photography. It was designed to describe the characteristics of this group of patients.
No interventions assigned to this group
Microvascular disease
Microvascular disease is an early characteristic of fundus changes in AIDS patients, with characteristic changes in fundus photography.
No interventions assigned to this group
uveitis
The uveitis patients in this study were mainly caused by treponema pallidum infection.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
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Zhongnan Hospital
OTHER
Responsible Party
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Locations
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Zhongnan Hospital
Wuhan, Hubei, China
Countries
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References
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Yen M, Chen J, Ausayakhun S, Kunavisarut P, Vichitvejpaisal P, Ausayakhun S, Jirawison C, Shantha J, Holland GN, Heiden D, Margolis TP, Keenan JD. Retinal detachment associated with AIDS-related cytomegalovirus retinitis: risk factors in a resource-limited setting. Am J Ophthalmol. 2015 Jan;159(1):185-92. doi: 10.1016/j.ajo.2014.10.014. Epub 2014 Oct 22.
De Cock KM, Jaffe HW, Curran JW. Reflections on 40 Years of AIDS. Emerg Infect Dis. 2021 Jun;27(6):1553-1560. doi: 10.3201/eid2706.210284.
Landovitz RJ, Scott H, Deeks SG. Prevention, treatment and cure of HIV infection. Nat Rev Microbiol. 2023 Oct;21(10):657-670. doi: 10.1038/s41579-023-00914-1. Epub 2023 Jun 21.
Bekker LG, Beyrer C, Mgodi N, Lewin SR, Delany-Moretlwe S, Taiwo B, Masters MC, Lazarus JV. HIV infection. Nat Rev Dis Primers. 2023 Aug 17;9(1):42. doi: 10.1038/s41572-023-00452-3.
Cohn LB, Chomont N, Deeks SG. The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies. Cell Host Microbe. 2020 Apr 8;27(4):519-530. doi: 10.1016/j.chom.2020.03.014.
Other Identifiers
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20231119
Identifier Type: -
Identifier Source: org_study_id
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