Lymphatic System Reflux After Lymphatic Operation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

79 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-01

Study Completion Date

2023-12-30

Brief Summary

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This study aimed to determine the impact on outcomes when recipient veins with reflux were used for LVA for the treatment of unilateral lower limb lymphedema.

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Detailed Description

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The use of recipient veins with reflux for lymphaticovenous anastomosis (LVA) is discouraged because of the common belief that it may lead to venous-lymphatic reflux (VLR), a phenomenon in which venous blood is refluxed into the lymphatic lumen after anastomosis, which can lower the long-term patency rate. However, this concept has yet to be validated.

Conditions

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Lymphedema

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Lower Limb Lymphedema

Patients with cancer-related unilateral lower limb lymphedema were enrolled.

Veins with reflux

Intervention Type OTHER

This group included patients who used only recipient veins with reflux

Reflux-free recipient veins

Intervention Type OTHER

This group included patients who utilized only reflux-free recipient veins

Interventions

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Veins with reflux

This group included patients who used only recipient veins with reflux

Intervention Type OTHER

Reflux-free recipient veins

This group included patients who utilized only reflux-free recipient veins

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* This study including patients diagnosed with lymphatic-related diseases at Kaohsiung Chang Gung Memorial Hospital from October 1, 2015, to December 31, 2022.
* Patients who underwent LVA for unilateral lower-limb lymphedema.