Etiology Of Recurrent Varicose Veins After Stripping Or Ablation Of Superficial Venous System

NCT ID: NCT05693350

Last Updated: 2023-01-23

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-03-01
• Study Completion Date: 2025-01-01

Brief Summary

Number of patients and causes and patterns of recurrent varicose veins in the lower limbs in patients with history of varicose veins stripping or ablation of the superficial venous system.

Detailed Description

Recurrence of varicose veins following surgery is a common, complex and costly problem in vascular surgery. Despite improvements in preoperative evaluation and methods of treatment, recurrence following varicose vein surgery is reported to occur in between 20 and 80% of cases. Many theories have been put forward concerning the underlying mechanisms and causes. These include poor understanding of the venous anatomy and haemodynamics, inadequate preoperative assessment, inappropriate or incomplete surgery and development of new sites of venous reflux as a consequence of disease progression or neovascularisation. However, it is difficult to evaluate these suggestions since the studies from which they arise vary greatly in their definitions of recurrence, preoperative assessment, initial treatment, classification and method and duration of follow-up.

Conditions

Recurrent Varicose Vein of Lower Limb (Disorder)

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

DUS

Duplex ultrasound

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• 1) Ages eligible for the study: 18-60. 2) Sexes eligible for the study: All. 3) Patients with previous intervention for varicose veins. 4) Patients with primary or secondary varicosities. 5) Patient's compliance to follow-up.

Exclusion Criteria

1) Patients with no history of interventions for varicose veins. 2) Patients treated with injection sclerotherapy alone. 3) Pregnant women. 4) Patients with arterial disease in the same limb (ABI <0.8). 5) Patients with post-thrombotic syndrome

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• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Mohamed Tarek Mostafa

Resident Doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Mohamed Tarek Mostafa, Resident doctor

Role: CONTACT

mtarekmostafa96@gmail.com

01116697331 ext. 002

References

Kostas T, Ioannou CV, Touloupakis E, Daskalaki E, Giannoukas AD, Tsetis D, Katsamouris AN. Recurrent varicose veins after surgery: a new appraisal of a common and complex problem in vascular surgery. Eur J Vasc Endovasc Surg. 2004 Mar;27(3):275-82. doi: 10.1016/j.ejvs.2003.12.006.

Reference Type: BACKGROUND

PMID: 14760596 (View on PubMed)

Blomgren L, Johansson G, Dahlberg-AKerman A, Noren A, Brundin C, Nordstrom E, Bergqvist D. Recurrent varicose veins: incidence, risk factors and groin anatomy. Eur J Vasc Endovasc Surg. 2004 Mar;27(3):269-74. doi: 10.1016/j.ejvs.2003.12.022.

Reference Type: BACKGROUND

PMID: 14760595 (View on PubMed)

Hamdan A. Management of varicose veins and venous insufficiency. JAMA. 2012 Dec 26;308(24):2612-21. doi: 10.1001/jama.2012.111352.

Reference Type: BACKGROUND

PMID: 23268520 (View on PubMed)

Other Identifiers

Recurrent Varicose Veins

Identifier Type: -

Identifier Source: org_study_id