Tracking a Tactile Signal Along the Nervous System

NCT ID: NCT06231810

Last Updated: 2025-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-29

Study Completion Date

2028-07-01

Brief Summary

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Quantify the flow of a tactile signal from the stimulus at the finger at the peripheral nervous system (PNS), to the central nervous system (CNS), and to cognitive perception at the brain in young adults (Aim 1) and individuals with and without stroke (Aim 2).

Detailed Description

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Conditions

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Stroke Tactile Perception

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Stimulus magnitude

Differing levels of tactile stimulus will be applied

Group Type EXPERIMENTAL

Tactile stimulation

Intervention Type BEHAVIORAL

Tactile stimuli of differing magnitudes will be applied

Interventions

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Tactile stimulation

Tactile stimuli of differing magnitudes will be applied

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

-right-hand dominance for participants who are neurotypical

For Aim 1:

-age range of 18-23

For Aim 2:

* participants who are neurotypical will be a similar age to the participants with stroke
* participants who are neurotypical will have no musculoskeletal and neurological conditions
* participants with stroke will have a single stroke incident resulting in a unilateral lesion (ischemic and hemorrhagic)
* participants with stroke will be in the chronic phase (\>1 year from stroke onset)
* participants with stroke will have an onset of stroke after the age of 18
* participants with stroke who meet the criteria of having the capacity to provide informed consent, regardless of aphasia

Exclusion Criteria

* minors
* pregnant women
* prisoners
* adults not capable of consenting on their own behalf.

For Aim 2:

* participants with stroke who have used antispastic injections in the past six months
* participants with stroke who have a lesion in the brainstem and/or cerebellum
* participants with stroke who have a stroke arising due to brain surgery
* participants with stroke who have hemineglect
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Virginia Polytechnic Institute and State University

OTHER

Sponsor Role lead

Responsible Party

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Netta Gurari

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Netta Gurari, PhD

Role: PRINCIPAL_INVESTIGATOR

Virginia Polytechnic Institute and State University

Locations

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Virginia Tech

Blacksburg, Virginia, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Netta Gurari, PhD

Role: CONTACT

Phone: 540-231-3073

Email: [email protected]

Facility Contacts

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Netta Gurari

Role: primary

Other Identifiers

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23-1256

Identifier Type: -

Identifier Source: org_study_id