Study Results
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Basic Information
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COMPLETED
NA
66 participants
INTERVENTIONAL
2017-01-11
2022-06-13
Brief Summary
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The clinical diagnosis of brain death should be supported by ancillary tests that provide information about cerebral blood flow or electrical activity in the brain. Some of the ancillary tests that evaluate cerebral blood flow include transcranial Doppler ultrasonography (TDUS), computed tomography (CT) angiography (CTA), and catheter-based cerebral angiography.
This study hypothesized that Orbital Doppler ultrasonography (ODUS) alone is more effective than TDUS in detecting intracranial blood flow in diagnosing brain death. To this end, the investigators examined the results of ODUS in patients diagnosed as brain dead who underwent CT angiography.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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ODUS
Orbital Doppler ultrasonography (ODUS)
Patients in whom brain death was suspected and the diagnostic procedure was initiated underwent ODUS .ODUS were performed during the apnoea test and the first neurological examination. At the second neurological examination at 12 hours, ODUS were repeated.
Orbital Doppler ultrasonography
During measurement, Doppler settings were adjusted to detect low flow and the smallest available Doppler gate was used for all ODUS examinations. The imaging probe position for ODUS was used transversely and axially, and mean values were recorded. ODUS 10-18 MHz linear probe was used.
Transcranial Doppler ultrasonography
During the measurement, Doppler settings were adjusted to detect low flow, and the minor available Doppler gate was used for all TDUS examinations. For TDUS, a temporal window was used approximately 1 cm above the midpoint of the line joining the lateral palpebral fissure and the external auditory meatus.
Transcranial Doppler ultrasonography ( TDUS) 3-5 MHz convex array probe was used.
Computed Tomography Angiography
Cranial Computed Tomography Angiography
Interventions
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Orbital Doppler ultrasonography
During measurement, Doppler settings were adjusted to detect low flow and the smallest available Doppler gate was used for all ODUS examinations. The imaging probe position for ODUS was used transversely and axially, and mean values were recorded. ODUS 10-18 MHz linear probe was used.
Transcranial Doppler ultrasonography
During the measurement, Doppler settings were adjusted to detect low flow, and the minor available Doppler gate was used for all TDUS examinations. For TDUS, a temporal window was used approximately 1 cm above the midpoint of the line joining the lateral palpebral fissure and the external auditory meatus.
Transcranial Doppler ultrasonography ( TDUS) 3-5 MHz convex array probe was used.
Computed Tomography Angiography
Cranial Computed Tomography Angiography
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* uncontrolled diabetes mellitus,
* facial trauma,
* hypothermia,
* hypotension (systolic pressure \< 100 mm Hg)
* endocrine-metabolic coma
18 Years
90 Years
ALL
No
Sponsors
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Korgün Ökmen
OTHER_GOV
Responsible Party
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Korgün Ökmen
Principal Investigator
Principal Investigators
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Korgün Ökmen
Role: PRINCIPAL_INVESTIGATOR
Bursa Yuksek Ihtisas Training and Research Hospital
Locations
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University of Health Sciences,,Bursa Yuksek Ihtisas Training and Research Hospital,
Bursa, , Turkey (Türkiye)
Countries
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Other Identifiers
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2017-15 /33
Identifier Type: -
Identifier Source: org_study_id
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