Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
49 participants
INTERVENTIONAL
2021-03-05
2023-06-30
Brief Summary
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Detailed Description
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Healthy women participants, after their consent, received secretome injections in their hands, face, and neck. Outcomes were assessed on the Hand Volume Rating Scale, Wrinkle Severity Rating Scale, and through histologic examination of skin biopsy at two different times: before treatment and after 12 months. A digital camera was used to obtain photographs of hands, face, and Neck at each visit. These were assessed by a single-blinded dermatologist. SPSS software version 26 (64-bit) was used for all analyses.
Participants provided written informed consent and were asked not to change their routine skin care habits during the study.
Conditions
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Study Design
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RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Umbilical cord (UC)- mesenchymal stem cells (MSCs) secretome
19 participants received UC-MSCs secretome injections in the neck and different areas of the face including the forehead, cheeks, under eyes, chin, and nasolabial folds.
secretome
The secretome is the secretions of MSCs or explants from umbilical cord tissues. It contains diverse trophic molecules including cytokines, chemokines, angiogenic factors, and growth factors.
UC-explants secretome
30 participants received UC-explants secretome in the left and right hands
secretome
The secretome is the secretions of MSCs or explants from umbilical cord tissues. It contains diverse trophic molecules including cytokines, chemokines, angiogenic factors, and growth factors.
Interventions
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secretome
The secretome is the secretions of MSCs or explants from umbilical cord tissues. It contains diverse trophic molecules including cytokines, chemokines, angiogenic factors, and growth factors.
Eligibility Criteria
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Inclusion Criteria
* any skin type according to the Glogau scale
* Willing to be a research subject, sign a consent form, and commit to follow-up visits
Exclusion Criteria
* patients using other anti-aging treatments within 1 month
25 Years
FEMALE
Yes
Sponsors
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COR clinic of Regenerative Medicine
NETWORK
Responsible Party
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Nada Alaaeddine
Dean of health Sciences at MUBS
Principal Investigators
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Nada Alaaeddine, PhD
Role: PRINCIPAL_INVESTIGATOR
COR clinic of Regenerative Medicine
Locations
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COR clinic of Regenerative Medicine
Beirut, , Lebanon
Countries
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Other Identifiers
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S2021-cor001
Identifier Type: -
Identifier Source: org_study_id
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