ctDNA and MRI Parameters in Head and Neck Cancer

NCT ID: NCT06215612

Last Updated: 2024-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-29

Study Completion Date

2030-02-28

Brief Summary

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Patients undergoing primary radiochhemotherapy for locally advanced head and neck squamous cell carcinomas are included in this study. In addition to standard of care treatment patients will undergo addiational blood draws and MR imaging studies. Circulating cell free tumor DNA will be analysed in the blood samples. BIological data, imaging data and clinical data (such as patient and tumor characteristics, oncologic outcome, side effects) will be analysed in a biomathematical modelling approach.

Detailed Description

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Conditions

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Head and Neck Neoplasms Carcinoma, Squamous

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Interventions

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Blood draw, MRI

Blood draw, MRI

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Squamous cell carcinoma head and neck
* Planned primary platinum based radiochemotherapy
* ECOG 0-2

Exclusion Criteria

* Palliative therapy intent
* Not MR eligible
Minimum Eligible Age

19 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Franziska Eckert

OTHER

Sponsor Role lead

Responsible Party

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Franziska Eckert

Deputy Head of Department

Responsibility Role SPONSOR_INVESTIGATOR

Central Contacts

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Franziska Eckert, M.D.

Role: CONTACT

+43-1-40400-26920

Other Identifiers

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1452/2023

Identifier Type: -

Identifier Source: org_study_id

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