The Fit With Us Study

NCT ID: NCT06207084

Last Updated: 2026-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

257 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-09-01

Study Completion Date

2029-02-01

Brief Summary

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The purpose of this 32-week study is to use an innovative experimental design known as SMART (Sequential Multiple Assignment Randomized Trial), which will allow us to determine the best way to sequence the delivery of teleexercise (referred to as an adaptive intervention), combined with predictive analytics on participant adherence in a stepped program of physical activity interventions. All 257 participants will have access to a library of recorded video exercise content, and a weekly wellness article. Some participants will receive health coaching calls (1st randomization). Analytic data will be used to determine which participants are responding or not responding to the intervention. Participants not responding after 4 weeks will receive either live one-on-one or group exercise training (2nd randomization). After 8 weeks, the participant will receive only pre-recorded exercise content and articles for a 24-week maintenance phase (weeks 9-32). The study outcomes are: The effectiveness of the adaptive interventions; Exploring mediating and moderating variables; Sensitivity analysis of the predictive analytics.

Detailed Description

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The proposed Sequential Multiple Assignment Randomized Trial (SMART) study seeks to develop an effective 32-week, resource sensitive strategy to improve physical activity levels in people with mobility impairments.

During the run-In period before the start of the intervention, interested individuals will consent to be part of the study. Once providing consent, Participants will respond to a baseline survey packet through REDCap. Participants must also complete a welcome call and set up an online account. Additionally, during the run-in period, the research team will ship an exercise tracker device, and an exercise band for the participant to wear during the intervention. The participant will receive an orientation call to assist them with using the website, setting up their exercise tracking device, and linking the device to the website. (see attached call outline)

After the run-in period, participants will be randomized into 1 of 2 groups: Asynchronous Exercise Program (AEP) and AEP + Smart Health Coaching (SHC). Finally, participants will be given access to the FitWithUs online platform, hosted on UAB servers, to access all the exercise content (exercise videos and articles). All participants will receive at least one new health and wellness article per week for eight weeks, and new exercise videos for 16 weeks.

The Adoption Phase will be split into two 4-week phases: early adoption (weeks 1 to 4) and late adoption (weeks 5 to 8). Participants in both groups will engage in pre-recorded exercise content. The AEP + SHC group may receive up to 12 health coaching calls. Machine learning will be used in Weeks 2, 6, and 10 to predict which AEP + HC participants should receive coaching calls for the next four weeks.

The proposed Sequential Multiple Assignment Randomized Trial (SMART) study seeks to develop an effective 32-week, resource-sensitive strategy to improve physical activity levels in people with mobility impairments. During the run-in period before the start of the intervention, interested individuals will consent to be part of the study. Once providing consent, participants will respond to a baseline survey packet through REDCap. Participants must also complete a welcome call and set up an online account. Additionally, during the run-in period, the research team will ship an exercise tracker device, and an exercise band for the participant to wear during the intervention. The participant will receive an orientation call to assist them with using the website, setting up their exercise tracking device, and linking the device to the website. After the run-in period, participants will be randomized into 1 of 2 groups: Asynchronous Exercise Program (AEP) and AEP + Smart Health Coaching (SHC). Finally, participants will be given access to the FitWithUs online platform, hosted on UAB servers, to access all the exercise content (exercise videos and articles). All participants will receive at least one new health and wellness article per week for eight weeks, and new exercise videos for 16 weeks. This intervention will be administered in 8 waves of \~33-34 participants each (pilot wave data excluded from analyses). The Adoption Phase will be split into two 4-week phases: early adoption (weeks 1 to 4) and late adoption (weeks 5 to 8). Participants in both groups will engage in pre-recorded exercise content. The AEP + SHC group may receive up to 12 health coaching calls. Machine learning will be used in Weeks 2, 6, and 10 to predict which AEP + HC participants should receive coaching calls for the next four weeks. At the end of the early adoption phase, the participant will complete a short set of questions (See week 4 questionnaire) the research team will classify participants in both groups into either a responder or a non-responder. If a participant is a responder, they will continue with their group assignment through the late adoption phase (AEP only or AEP + SHC). If the participant is a non-responder, they will be randomized a second time into 1 of 2 sub-groups: Live 1-on-1 training or Live group training for the late adoption phase. All live training will occur remotely through ZOOM. Participants in non-responder sub-groups will be asked to participate in their respective live training up to 3 times per week for weeks 5 to 8. This second randomization results in six possible intervention groups: 1) AEP only responder, 2) AEP + HC responder, 3) AEP non-responder + LAT\_1-1, 4) AEP non-responder + LAT\_GRP, 5) AEP + HC non-responder + LAT\_1-1, 6) AEP + HC non-responder + LAT\_GRP. Upon finishing the late adoption phase, all participants will complete another survey packet and a semi-structured interview (see interview guide), and receive AEP only for a 24-week maintenance phase (weeks 9-32). Upon completion of week 32, the participant will complete a final survey packet. Throughout the study, we will be collecting data from the participant's exercise tracker. These data include steps and minutes of activity/inactivity. During weeks 9 to 32, participants will have open access to the website and its library of exercise content. The research team will continue to collect activity data and website analytics (for example video watch minutes). Participants may receive a reminder call to complete surveys. We will use the following validated measures: \[existing measures list unchanged\].

Conditions

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Mobility Limitations Disability Physical Telehealth Health Coaching Physical Activity Behavior, Health eHealth Health Literacy Self Efficacy Fatigue Usability Predictive Model

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Sequential Multiple Assignment Randomization Model
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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asynchronous exercise responder

Individuals only receiving asynchronous exercise content and are responding

Group Type EXPERIMENTAL

asynchronous content only

Intervention Type BEHAVIORAL

Receives asynchronous exercise content and no live training

Asynchronous exercise and health coaching responder

Individuals receiving asynchronous exercise content and health coaching and are responding

Group Type EXPERIMENTAL

Asynchronous content and health coaching and no live training

Intervention Type BEHAVIORAL

Receives asynchronous content, health coaching and no live training.

Asynchronous exercise non-responder and 1 on 1 live training

Individuals receiving asynchronous exercise content and are not responding. The are receiving 1 on 1 live exercise sessions.

Group Type EXPERIMENTAL

asynchronous content only and 1 on 1 live training

Intervention Type BEHAVIORAL

receives asynchronous content and live 1 on 1 training

Asynchronous exercise and health coaching non-responder and 1 on 1 live training

Individuals receiving asynchronous exercise content and health coaching and are not responding. The are receiving 1 on 1 live exercise sessions.

Group Type EXPERIMENTAL

asynchronous content and health coaching and 1 on 1 training

Intervention Type BEHAVIORAL

receives asynchronous content, health coaching, and live training

Asynchronous exercise non-responder and group live training

Individuals receiving asynchronous exercise content and are not responding. The are receiving group live exercise sessions.

Group Type EXPERIMENTAL

asynchronous content and group training

Intervention Type BEHAVIORAL

receives asynchronous content and live group training

Asynchronous exercise and health coaching non-responder and group live training

Individuals receiving asynchronous exercise content and health coaching and are not responding. The are receiving group live exercise sessions.

Group Type EXPERIMENTAL

Asynchronous content and health coaching and group training

Intervention Type BEHAVIORAL

receives asynchronous content, health coaching, and live group training

Interventions

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asynchronous content only

Receives asynchronous exercise content and no live training

Intervention Type BEHAVIORAL

Asynchronous content and health coaching and no live training

Receives asynchronous content, health coaching and no live training.

Intervention Type BEHAVIORAL

asynchronous content only and 1 on 1 live training

receives asynchronous content and live 1 on 1 training

Intervention Type BEHAVIORAL

asynchronous content and health coaching and 1 on 1 training

receives asynchronous content, health coaching, and live training

Intervention Type BEHAVIORAL

asynchronous content and group training

receives asynchronous content and live group training

Intervention Type BEHAVIORAL

Asynchronous content and health coaching and group training

receives asynchronous content, health coaching, and live group training

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Participants are excluded from participation if they (1) possess significant visual acuity that prevents seeing a computer screen to follow a home exercise program; (2) have been regularly engaging in exercise for the previous 3 months; (3) are unable to use their arms and their legs at all to exercise; (4) are unsafe to exercise; (5) self-report that they are currently pregnant
Minimum Eligible Age

18 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Alabama at Birmingham

OTHER

Sponsor Role lead

Responsible Party

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Mohanraj Thirumalai

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohanraj Thirumalai, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Alabama at Birmingham

Locations

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Wellness, Health and Research Facility

Birmingham, Alabama, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Mohanraj Thirumalai, PhD

Role: CONTACT

205-934-7189

Sangeetha Mohanraj, MS

Role: CONTACT

205-975-0550

Facility Contacts

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Ayse G Zengul, PhD

Role: primary

659 2733627

Related Links

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https://fitwithus.org/

Intervention landing page.

Other Identifiers

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90REGE0019

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

IRB-300011762

Identifier Type: -

Identifier Source: org_study_id

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