Cognitive Behavioral Therapy for Insomnia in Type 2 Diabetes Mellitus

NCT ID: NCT06202742

Last Updated: 2024-03-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-08

Study Completion Date

2025-06-30

Brief Summary

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This study will explore the effects of cognitive behavioral therapy for insomnia (CBTI) compare to health educations in patients with type 2 diabetes (T2DM) with insomnia symptoms.

Detailed Description

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This study will recruit participants with T2DM with insomnia symptoms and randomize them to weekly CBTI or health education for 8 weeks. Outcomes will be measured at baseline and 8 week, and 16 weeks (8 weeks post intervention).

Primary outcome will be subjective sleep quality as assessed by Pittsburgh Sleep Quality Index Secondary outcomes will be fasting glucose, hemoglobin A1C, insulin levels, high sensitivity c-reactive protein, objective sleep parameters from accelerometer, depressive symptoms, daytime sleepiness, quality of life, anxiety symptoms and stress symptoms.

Conditions

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Type 2 Diabetes Insomnia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Cognitive behavioral therapy

Cognitive behavioral therapy for insomnia (CBTI) is non-medical treatment to improve insomnia. CBTI group will attend online meeting, 1 hour weekly for 8 weeks.

Group Type EXPERIMENTAL

cognitive behavioral therapy for insomnia

Intervention Type BEHAVIORAL

Online meeting, weekly for 8 weeks, to deliver CBTI by psychologist/ psychiatrist

Health education

Health education group will attend online meeting, 1 hour weekly for 8 weeks.

Group Type ACTIVE_COMPARATOR

Health education

Intervention Type BEHAVIORAL

Online meeting, weekly for 8 weeks, to deliver general health knowledge

Interventions

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cognitive behavioral therapy for insomnia

Online meeting, weekly for 8 weeks, to deliver CBTI by psychologist/ psychiatrist

Intervention Type BEHAVIORAL

Health education

Online meeting, weekly for 8 weeks, to deliver general health knowledge

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Type 2 diabetes mellitus age 30 to 65 years old
* Hemoglobin A1C ≥ 6.5 but ≤ 10 %
* Have poor sleep quality as assessed by Insomnia Severity Index ≥ 15
* Receive the same hypoglycemic treatments 3 months before the intervention
* If using sleep aid, the dose needs to be stable for 3 months prior to the enrollment
* Ability to use the electronic devices (computer, tablet) and assess the internet
* Willing to attend all of the 8 sessions activities

Exclusion Criteria

* Type 1 diabetes mellitus
* Night shift work
* Insulin therapy
* Severe hypoglycemia who required hospitalization or emergency department visit in the past 6 months
* History of diabetic ketoacidosis in the past 6 months
* Medically unstable conditions eg. renal replacement therapy, liver failure, heart failure, active cancer, epilepsy, unstable cerebrovascular disease
* Psychosis, uncontrolled depression
* Untreated obstructive sleep apnea or STOP-BANG ≥ 5
* Language/communication/hearing/sight disability
* Pregnancy or lactation
* Care giver of infant
* Harmful alcohol/smoking (≥15 standard-drink in men and ≥8 standard-drink in women)
Minimum Eligible Age

30 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Similan Kirisri

Role: PRINCIPAL_INVESTIGATOR

Ramathibodi Hospital

Locations

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Faculty of Medicine Ramathibodi Hospital Mahidol University

Bangkok, , Thailand

Site Status RECRUITING

Countries

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Thailand

Central Contacts

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Similan Kirisri

Role: CONTACT

660805491645

Chutintorn Sriphrapradang

Role: CONTACT

660819876945

Facility Contacts

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Similan Kirisri

Role: primary

660805491645

Chutintorn Sriphrapradang

Role: backup

660819876945

Other Identifiers

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MURA2023/873

Identifier Type: -

Identifier Source: org_study_id

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