Cardiac Amyloidosis in HFpEF Tunisian Patients

NCT ID: NCT06201832

Last Updated: 2024-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

87 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-07-01

Study Completion Date

2024-12-31

Brief Summary

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Cardiac amyloidosis (CA) has recently been reported as a common cause of heart failure with preserved left ventricular ejection fraction (HFpEF), with a prevalence of 6% in elderly HFpEF patients. However, the diagnosis of CA is still challenging and requires multiple costly investigations.

Regardless of the type of CA, TTR or AL, early diagnosis significantly improves prognosis.

In this study, the investigators aimed to determine the prevalence of CA in Tunisian HFpEF patients and to identify clinical and ultrasound criteria predictive of CA.

Detailed Description

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Conditions

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Cardiac Amyloidosis Heart Failure With Preserved Ejection Fraction Echocardiography CMR Bone Scintigraphy Prevalence Diagnosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* HFpEF during the previous year
* IVS thickness of 12mm or greater

Exclusion Criteria

* age under 60 years
* Acute coronary syndrome complicated by HFpEF
* Congenital heart disease
Minimum Eligible Age

60 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Tunis El Manar

OTHER

Sponsor Role lead

Responsible Party

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Lilia Zakhama

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lilia Zakhama, Prof

Role: PRINCIPAL_INVESTIGATOR

University of Tunis El Manar, Faculty of Medicine of Tunis, Tunisia

Locations

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Security Hospital Forces

La Marsa, Tunis Governorate, Tunisia

Site Status RECRUITING

Countries

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Tunisia

Central Contacts

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Lilia Zakhama, Prof

Role: CONTACT

98345427 ext. +216

Facility Contacts

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Lilia Zakhama, Prof

Role: primary

98345427 ext. +216

Other Identifiers

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13-2023

Identifier Type: -

Identifier Source: org_study_id

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