Comparison of Aqueous Humor Adipokines in Glaucoma Patients and Healthy Controls

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

2 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-08

Study Completion Date

2024-04-01

Brief Summary

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The purpose of this study is to observe whether there are differences in adipokines in the aqueous humor between patients with primary open-angle glaucoma (POAG) and healthy controls

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Detailed Description

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1\. Inclusion criteria: Patients aged 18 years or older, diagnosed with primary open-angle glaucoma (POAG) and healthy controls (who underwent cataract surgery).

2\. Exclusion criteria:

1. Other Ocular Diseases: Patients with concurrent ocular diseases such as macular degeneration, retinal detachment, etc., are excluded.
2. Ocular Surgery History: individuals who have undergone intraocular or laser surgery within the past 6 months, except for uncomplicated cataract surgery.
3. History of Ocular Trauma or Inflammation
4. Systemic Diseases or Mental Disorders: Patients with systemic diseases(e.g., diabetes, rheumatoid arthritis) and those with mental disorders are excluded.
5. Pregnancy or Lactation: Females who are pregnant or lactating are excluded.
6. Presence of any retinal or optic nerve disease other than glaucoma.

Conditions

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Glaucoma Adipokines

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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POAG Group

POAG patients who underwent filtering surgery, cataract surgery or MIGS.

none intervention

Intervention Type OTHER

This study has no intervention

Control Group

Healthy patients who underwent cataract surgery.

none intervention

Intervention Type OTHER

This study has no intervention

Interventions

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none intervention

This study has no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 years or older, diagnosed with primary open-angle glaucoma (POAG) and healthy controls (who underwent cataract surgery).

Exclusion Criteria

* Other Ocular Diseases: Patients with concurrent ocular diseases such as macular degeneration, retinal detachment, etc., are excluded.
* Ocular Surgery History: individuals who have undergone intraocular or laser surgery within the past 6 months, except for uncomplicated cataract surgery.
* History of Ocular Trauma or Inflammation
* Systemic Diseases or Mental Disorders: Patients with systemic diseases(e.g., diabetes, rheumatoid arthritis) and those with mental disorders are excluded.
* Pregnancy or Lactation: Females who are pregnant or lactating are excluded.
* Presence of any retinal or optic nerve disease other than glaucoma.

Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No