CT Imaging for Guiding PA-TACE for HCC

NCT ID: NCT06156748

Last Updated: 2025-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1770 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-01

Study Completion Date

2025-06-30

Brief Summary

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Postoperative adjuvant transarterial chemoembolization (PA-TACE) may improve survival outcomes in a subset of patients with resected hepatocellular carcinoma (HCC), reliable biomarkers for the criterion for the selection of candidates are lacking. The present study aimed to evaluate whether CT imaging can provide more value for predicting benefit from PA-TACE.

Detailed Description

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Conditions

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Carcinoma, Hepatocellular

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Hepatectomy alone

postoperative adjuvant transarterial chemoembolization

Intervention Type PROCEDURE

HCC patients received hepatectomy and PA-TACE.

PA-TACE

No interventions assigned to this group

Interventions

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postoperative adjuvant transarterial chemoembolization

HCC patients received hepatectomy and PA-TACE.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* CT scans acquired no more than one month before surgery
* Confirmation of HCC diagnosis by pathological examination
* Curative surgical resection

Exclusion Criteria

* Prior antitumor treatment
* Macrovascular thrombosis or metastasis
* Perioperative mortality
* Unqualified image artifacts
* Tumor rupture
* MVI status not reported
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zhujiang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Quan Xianyue

Academic Head of Department of Radiology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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ZhuJiang Hospital of Southern Medical University

Guangzhou, Guangdong, China

Site Status

Countries

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China

References

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Li X, Liang X, Li Z, Liang J, Qi Z, Zhong L, Geng Z, Liang W, Quan X, Liang C, Liu Z. A novel stratification scheme combined with internal arteries in CT imaging for guiding postoperative adjuvant transarterial chemoembolization in hepatocellular carcinoma: a retrospective cohort study. Int J Surg. 2024 May 1;110(5):2556-2567. doi: 10.1097/JS9.0000000000001191.

Reference Type DERIVED
PMID: 38377071 (View on PubMed)

Other Identifiers

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2019-KY-021-01

Identifier Type: -

Identifier Source: org_study_id

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