Efficacy of Different Types of Milk in Improving Sleep Quality in Subjects With Sleep Problems (Milca)

NCT ID: NCT06154616

Last Updated: 2024-02-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-15

Study Completion Date

2024-01-19

Brief Summary

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Randomized, controlled, double-blind intervention study, with four parallel branches depending on the product consumed, to analyze the efficacy of different types of milks on the improvement of sleep quality.

Detailed Description

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The duration of the study will be 90 days (12 weeks). Each day they will have to consume the product under investigation. The subjects who meet the selection criteria will be randomly distributed in each of the study groups (A, B, C or D, depending on the group in which they have been randomized). Each day the subjects will have to fill in a diary on sleep quality and concomitant medication.

They will make a total of two visits to the research laboratory and the tests preestablished in the protocol will be performed. Subsequently, a statistical analysis will be performed with the variables measured in the study to obtain the results.

Conditions

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Poor Quality Sleep

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Control

Subjects will consume 250 ml of milk half an hour before bedtime.

Group Type PLACEBO_COMPARATOR

Control Product

Intervention Type DIETARY_SUPPLEMENT

Lactose-free skimmed milk

Ashw 250

Subjects will consume 250 ml of milk half an hour before bedtime.

Group Type EXPERIMENTAL

Experimental Product: 250

Intervention Type DIETARY_SUPPLEMENT

Lactose-free skimmed milk enriched with 250 mg aswaghanda

Ashw 250 + TRP

Subjects will consume 250 ml of milk half an hour before bedtime.

Group Type EXPERIMENTAL

Experimental Product: 250 + TRP

Intervention Type DIETARY_SUPPLEMENT

Lactose-free skimmed milk enriched with 250 mg aswaghanda and tryptophan

Ashw 600

Subjects will consume 250 ml of milk half an hour before bedtime.

Group Type EXPERIMENTAL

Experimental Product: 600

Intervention Type DIETARY_SUPPLEMENT

Lactose-free skimmed milk enriched with 600 mg aswaghanda

Interventions

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Control Product

Lactose-free skimmed milk

Intervention Type DIETARY_SUPPLEMENT

Experimental Product: 250

Lactose-free skimmed milk enriched with 250 mg aswaghanda

Intervention Type DIETARY_SUPPLEMENT

Experimental Product: 250 + TRP

Lactose-free skimmed milk enriched with 250 mg aswaghanda and tryptophan

Intervention Type DIETARY_SUPPLEMENT

Experimental Product: 600

Lactose-free skimmed milk enriched with 600 mg aswaghanda

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy adults (\> 18 years).
* Low sleep quality by Pittsburgh Sleep Quality Questionnaire (PSQI).
* Volunteers able to understand the clinical study and willing to comply with the study procedures and requirements.

Exclusion Criteria

* Subjects with serious or terminal illnesses.
* Subjects with known allergy or hypersensitivity to any of the components of the investigational product.
* Participation in another study involving blood draws or dietary intervention.
* Subjects with body mass index above 32 kg/m2.
* Pregnant or lactating women.
* Use of medications that alter cognitive functions or sleep, such as barbiturates, anticonvulsants, benzodiazepines, antidepressants, neuroleptics, alcohol and illicit drugs.
* Organic dementias such as Alzheimer's, Huntington's disease, Parkinson's and senile dementia.
* Inability to understand informed consent (IC).
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad Católica San Antonio de Murcia

OTHER

Sponsor Role lead

Responsible Party

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Francisco Javier López Román

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Catholic University of Murcia

Murcia, , Spain

Site Status

Countries

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Spain

Other Identifiers

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UCAMCFE-00033

Identifier Type: -

Identifier Source: org_study_id

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