Nafamostat Efficacy in Phase 3 Registrational CRRT Study
NCT ID: NCT06150742
Last Updated: 2025-10-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
70 participants
INTERVENTIONAL
2024-08-15
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Niyad
1 mg/mL infusion of nafamostat mesylate
Niyad (nafamostat mesylate)
Niyad (nafamostat mesylate) lyophilized
Placebo
0.9% saline infusion
Placebo (0.9% NaCl)
0.9% NaCl
Interventions
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Niyad (nafamostat mesylate)
Niyad (nafamostat mesylate) lyophilized
Placebo (0.9% NaCl)
0.9% NaCl
Eligibility Criteria
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Inclusion Criteria
* Patients who cannot tolerate heparin or are at high risk of bleeding
Exclusion Criteria
* Patients receiving systemic anticoagulation
* Patients with active bleeding
18 Years
80 Years
ALL
No
Sponsors
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Talphera, Inc
INDUSTRY
Responsible Party
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Locations
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University of California Los Angeles
Los Angeles, California, United States
AdventHealth
Orlando, Florida, United States
Henry Ford Health
Detroit, Michigan, United States
University of New Mexico
Albuquerque, New Mexico, United States
Northwell Health
Great Neck, New York, United States
Mount Sinai
New York, New York, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
Medical University of South Carolina
Charleston, South Carolina, United States
Baylor University Medical Center
Dallas, Texas, United States
Countries
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Central Contacts
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Facility Contacts
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Senior Clinical Research Associate
Role: primary
Program Manager Study Intake
Role: primary
Clinical Study Coordinator
Role: primary
Nurse Research Coordinator
Role: primary
Clinical Research Coordinator
Role: primary
Clinical Research Assistant
Role: primary
Clinical Research Manager
Role: primary
Assistant Director, Laboratory Operations
Role: primary
Clinical Research Coordinator
Role: primary
Research Nurse 1
Role: primary
Other Identifiers
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NYD301
Identifier Type: -
Identifier Source: org_study_id
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