The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
NCT ID: NCT06138340
Last Updated: 2025-02-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
120 participants
OBSERVATIONAL
2023-08-31
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Dex group
Participants will be sedated and maintained by dexmedetomidine.
Dexmedetomidine
Participants will be sedated and maintained by dexmedetomidine during the surgery.
Propofol group
Participants will be sedated and maintained by propofol.
Propofol
Participants will be sedated and maintained by propofol during the surgery.
Remimazolam group
Participants will be sedated and maintained by remimazolam.
Remimazolam Injection
Participants will be sedated and maintained by remimazolam during the surgery.
Interventions
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Dexmedetomidine
Participants will be sedated and maintained by dexmedetomidine during the surgery.
Propofol
Participants will be sedated and maintained by propofol during the surgery.
Remimazolam Injection
Participants will be sedated and maintained by remimazolam during the surgery.
Eligibility Criteria
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Inclusion Criteria
* Selective operation
* Age over 18 years old
* ASA I-II
* Right handedness
Exclusion Criteria
* History of intracranial surgery
* Drug and/or alcohol abuse
* History of dementia or mental illness
* Pregnant or lactating women
* Contraindications for MRI
* Severe bradycardia (heart rate less than 40 beats per minute), sick sinus syndrome or second-to-third degree atrioventricular block
* Severe hepatic or renal dysfunction
18 Years
ALL
No
Sponsors
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Beijing Tiantan Hospital
OTHER
Responsible Party
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Yuming Peng
Deputy chief of Department of Anesthesiology
Locations
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Beijing Tian Tan Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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20230808
Identifier Type: -
Identifier Source: org_study_id
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