Evaluation of the Consequences of Poly Vaccination on Innate Immunity : Applications to a Military Population

NCT ID: NCT06110741

Last Updated: 2023-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

410 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-30

Study Completion Date

2026-04-30

Brief Summary

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In this study, the poly vaccination of military personnel prior to deployment will be analyzed in terms of central, peripheral and long-lasting changes in innate immunity.

Analysis of monocyte immune training induced by vaccination will provide a better understanding of the indirect effects of vaccination and their persistence over time.

Detailed Description

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Conditions

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Vaccine Breakthrough Infections

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Sampling and survey group

This group will complete questionnaires and participate in sample collection.

Blood and saliva sampling

Intervention Type OTHER

Collecting blood and saliva sample

Survey

Intervention Type OTHER

Collecting data on infectious diseases during the study period

Survey group

This group will only complete questionnaires

Survey

Intervention Type OTHER

Collecting data on infectious diseases during the study period

Interventions

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Blood and saliva sampling

Collecting blood and saliva sample

Intervention Type OTHER

Survey

Collecting data on infectious diseases during the study period

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* french military personnel
* \>18yo
* overseas deployment scheduled between 30 and 60 days after vaccination session
* adult
* able to give consent

Exclusion Criteria

* unrectified military personnel
* having received a live vaccine within 6 months prior to inclusion
* having received an attenuated vaccine within 3 months prior to inclusion
* pregnancy or breastfeeding
* vaccine contraindication
* major incapacity
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Direction Centrale du Service de Santé des Armées

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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2023-A01356-39

Identifier Type: OTHER

Identifier Source: secondary_id

2023PPRC01

Identifier Type: -

Identifier Source: org_study_id

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