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A Study To Examine Serologic Response In Hospitalized Patients Receiving Polyvalent Pneumococcal Vaccine

NCT ID: NCT00955851

Last Updated: 2010-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-06-30

Study Completion Date

2010-07-31

Brief Summary

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Investigators in the Division of Infectious Diseases and the Division of Hospital Medicine of The George Washington University Medical Center are carrying out a study to determine if hospitalized patients receiving the polyvalent pneumococcal vaccine during an acute illness develop an adequate antibody response. The study group will consist of individuals diagnosed with pneumonia and admitted to the Medicine ward under the Pneumonia Core Measure Protocol, which assigns appropriate patients for vaccination based on the current guidelines from the Advisory Committee on Immunization Practices (ACIP).

Detailed Description

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Conditions

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Pneumonia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Pneumonia patients

The study group will consist of individuals diagnosed with pneumonia and admitted to the Medicine ward under the Pneumonia Core Measure Protocol.

Pre and post vaccination titers

Intervention Type OTHER

Titers will be obtained pre vaccination and 4 weeks post vaccination

Interventions

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Pre and post vaccination titers

Titers will be obtained pre vaccination and 4 weeks post vaccination

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Males or female patients ages 18 or older
* Diagnosis of pneumonia requiring hospitalization
* Admission to the Medicine Ward under the Pneumonia Core Measure protocol
* Eligible to receive standard of care pneumococcal vaccine by the treating physician
* Able to receive an injection
* Able to provide informed consent

Exclusion Criteria

* Preexisting history of immunosuppression, to include any of the following: HIV/AIDS, Chronic corticosteroid use, Malignancy requiring myeloablative chemotherapy, Hematologic malignancy, History of solid organ or stem cell transplant
* Pregnancy
* Receipt of pneumococcal vaccine within the last 5 years
* Prior history of hypersensitivity reaction to the vaccine
* Unable to return for follow-up testing
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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George Washington University

OTHER

Sponsor Role lead

Responsible Party

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George Washington University Medical Faculty Associates

Locations

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George Washington University Hospital

Washington D.C., District of Columbia, United States

Site Status

Countries

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United States

Other Identifiers

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010902

Identifier Type: -

Identifier Source: org_study_id