Assessment of the Increased Risk of Infection Following an Ultratrail

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

1300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-31

Study Completion Date

2023-12-31

Brief Summary

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The increase in the practice of running has encouraged a proliferation of studies evaluating the impact of this sport on health. A number of these studies have looked at the influence of endurance events on the immune system. After prolonged exercise, a systemic inflammatory syndrome sets in, with repercussions for the functioning of the immune system. The number of lymphocytes in the blood is reduced, the function of natural killer (NK) cells is impaired and secretory immunity is impaired. During this period of immunosuppression, often referred to as the 'open window', the host may be more susceptible to micro-organisms that bypass the first line of defence.

The invetigators' hypothesis is therefore that ultratrailers are overexposed to the risk of infection due to immunodepression resulting from practising this sport. In order to support this hypothesis, the investigators would like to look at infectious complications in general and ear-nose and throat episodes (rhinitis, pharyngitis, laryngitis, etc.) in particular, which are the most common infections encountered in primary care, along with urinary tract infections.

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Detailed Description

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Conditions

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Running Immune Deficiency Infections

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

This study is a descriptive cohort study comparing the occurrence of infection between exposed (runners of an ultra-trail) and unexposed subjects (their companions).

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Exposed (Runners)

Ultra-endurance runners taking part in an ultra-trail of 72 km, 109 km or 165 km

Group Type EXPERIMENTAL

Ultra-trail

Intervention Type OTHER

Questionnaires sent to runners at various pre-race and post-race times (Day3, Day6, Day10, Day14 and Day21)

Non-exposed (companions)

Runners' companions not running

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Ultra-trail

Questionnaires sent to runners at various pre-race and post-race times (Day3, Day6, Day10, Day14 and Day21)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* \> 18 years
* Participating in a Grand Raid de la Réunion 2023 race (Mascareignes, Trail de Bourbon, Diagonale des Fous)
* Have a companion living under the same roof during the week preceding the race and the 21 days following the race and who agrees to answer the questionnaires
* Do not object to the research