Comparison of Outcomes Between Warshaw and Kimura Techniques for Spleen-preserving Minimally Invasive Distal Pancreatectomy

NCT ID: NCT06084975

Last Updated: 2023-10-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

314 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-07-01

Study Completion Date

2022-12-31

Brief Summary

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Spleen-persevering distal pancreatectomy (SP-DP) has been widely advocated as a routine procedure for benign or low-grade malignant tumors in the pancreatic body and tail, especially with a minimally invasive approach. Spleen preservation can be accomplished with Kimura technique (KT) or Warshaw technique (WT) Both of the two techniques were proved to be feasible and efficient. However, the perioperative outcomes and long-term benefits between patients with KT and WT in spleen-persevering minimally invasive distal pancreatectomy (SP-MIDP) remains controversial.

Several small series have reported a slightly higher prevalence of postpancreatectomy hemorrhage (PPH) in patients who undergo KT than those undergo WT. The exposure of splenic vessels to erosive pancreatic juice and the preservation of splenic vessels itself may explain the higher chance of PPH in KT. Larger volume studies are warranted to confirm this finding and to clarify the clinical significance. This study compared the perioperative outcomes between the two spleen-preserving techniques, with a focus on parameters relating to perioperative patient safety. Especially, the incidence and clinical relevance of PPH in SP-MIDP were evaluated.

Detailed Description

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Conditions

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Distal Pancreatectomy Spleen Preservation Postpancreatectomy Hemorrhage

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Kimura technique (KT)

Spleen preservation is accomplished by sparing the splenic vessels.

Splenic vessels preservation

Intervention Type PROCEDURE

preservation the splenic vessels

Warshaw technique (WT)

Spleen preservation is accomplished by sacrificing the splenic vessels and maintaining vascularity through the preserved short gastric and left gastroepiploic vessels.

No interventions assigned to this group

Interventions

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Splenic vessels preservation

preservation the splenic vessels

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* pathological diagnosis of benign or low-grade malignant pancreas tumors.

Exclusion Criteria

* incomplete medical records,
* history of previous splenectomy,
* high-grade malignant pancreas tumors,
* conversion to open DP (ODP).
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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TingBo Liang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Liang Tingbo

Role: PRINCIPAL_INVESTIGATOR

Zhejiang University

Locations

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the First Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China

Site Status

Countries

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China

Other Identifiers

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SP-MIDP

Identifier Type: -

Identifier Source: org_study_id

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