Peri-operative Expression Analysis of Pancreatic Stone Protein in a Surgical Study Population

NCT ID: NCT01258179

Last Updated: 2018-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-02-28

Study Completion Date

2017-12-31

Brief Summary

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The purpose of this study is to analyze the peri-operative expression of pancreatic stone protein and pancreatitis-associated protein in surgical patients following major abdominal surgery by blood samples.

Detailed Description

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Conditions

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Patients Undergoing Major Abdominal Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Sepsis Group

Patients suffering from sepsis in the postoperative course after major abdominal surgery

Analysis of PSP and PAP from venous blood samples

Intervention Type OTHER

to analyse the peri-operative expression of pancreatic stone protein in surgical patients following major abdominal surgery

Control Group

Patients without suffering sepsis during postoperative follow up after major abdominal surgery

Analysis of PSP and PAP from venous blood samples

Intervention Type OTHER

to analyse the peri-operative expression of pancreatic stone protein in surgical patients following major abdominal surgery

Interventions

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Analysis of PSP and PAP from venous blood samples

to analyse the peri-operative expression of pancreatic stone protein in surgical patients following major abdominal surgery

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* abdominal major surgery
* need for post-operative ICU care

Exclusion Criteria

\- patients who do not agree the written informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Christian E Oberkofler, MD

Role: PRINCIPAL_INVESTIGATOR

UniversitaetsSpital Zuerich

Locations

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Department of Visceral and Transplantation Surgery

Zurich, CH/Zürich, Switzerland

Site Status

Countries

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Switzerland

References

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Fisher OM, Raptis DA, Vetter D, Novak A, Dindo D, Hahnloser D, Clavien PA, Nocito A. An outcome and cost analysis of anal fistula plug insertion vs endorectal advancement flap for complex anal fistulae. Colorectal Dis. 2015 Jul;17(7):619-26. doi: 10.1111/codi.12888.

Reference Type DERIVED
PMID: 25641401 (View on PubMed)

Fisher OM, Oberkofler CE, Raptis DA, Soll C, Bechir M, Schiesser M, Graf R. Pancreatic stone protein (PSP) and pancreatitis-associated protein (PAP): a protocol of a cohort study on the diagnostic efficacy and prognostic value of PSP and PAP as postoperative markers of septic complications in patients undergoing abdominal surgery (PSP study). BMJ Open. 2014 Mar 6;4(3):e004914. doi: 10.1136/bmjopen-2014-004914.

Reference Type DERIVED
PMID: 24604486 (View on PubMed)

Other Identifiers

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11.2009

Identifier Type: -

Identifier Source: org_study_id

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