GENomic PROfilation for Therapeutic Purposes in SARComas and Molecular Tumor Board (MTB): Retrospective/Prospective Study in Referral Centers

NCT ID: NCT06076070

Last Updated: 2023-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-05-25

Study Completion Date

2024-05-25

Brief Summary

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Multicenter noninterventional, translational study, retrospective/prospective designed in order to assess the aptitude to the use of genomic profiling methods for therapeutic purposes and evaluation by the institutional Molecular Tumor Board (MTB) of sarcoma patients with metastatic/locally advanced disease that is inoperable with no viable therapeutic alternatives or with histotypes known to be resistant to available in-label medical treatments and without already therapeutically validated driver mutations.

Detailed Description

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Conditions

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Sarcoma

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Sarcoma patients of any age (inclusion of centers pediatric)
* Patients with any histotype of soft tissue sarcomas and bone
* Patients at any stage of the treatment pathway for disease that is localized or metastatic/inoperable
* Availability of follow-up data
* Written informed consent (prospective part/patients in follow-up)
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Candiolo Cancer Institute - IRCCS

OTHER

Sponsor Role collaborator

Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale

NETWORK

Sponsor Role collaborator

Istituto Oncologico Veneto IRCCS

OTHER

Sponsor Role collaborator

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

OTHER

Sponsor Role collaborator

Istituto Ortopedico Rizzoli

OTHER

Sponsor Role collaborator

Ospedale Pediatrico Bambin Gesù

OTHER

Sponsor Role collaborator

IRCCS Azienda Ospedaliero-Universitaria di Bologna

OTHER

Sponsor Role collaborator

Istituti Tumori Giovanni Paolo II

NETWORK

Sponsor Role collaborator

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS

OTHER

Sponsor Role collaborator

Regina Elena Cancer Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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"Regina Elena" National Cancer Institute

Rome, , Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Virginia Ferraresi, MD

Role: CONTACT

0652665144

Facility Contacts

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Virginia Ferraresi, MD

Role: primary

0652665144

Other Identifiers

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RS1607/21

Identifier Type: -

Identifier Source: org_study_id

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