Orthosis to Improve Trunk Control in Infants Age 6-18 Months

NCT ID: NCT06027580

Last Updated: 2026-01-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-02-21

Study Completion Date

2026-08-06

Brief Summary

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The purpose of this study is to determine the impact of the SPIO® Core-MAX® Expedition orthosis on an infant's head, trunk and upper limb function.

Detailed Description

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This study will observe the difference in outcomes between two courses of standard clinical care: therapy or therapy with the SPIO® Core-MAX® Expedition orthosis. Families will self-select that standard care option that works best for their family, and outcomes will be observed at baseline, 3 months and 6 months.

Conditions

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Cerebral Palsy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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SPIO group

Standard Care Therapy option 1: parents may self-select this standard care combined option of therapy and use of SPIO® Core-MAX® Expedition thoracolumbosacral orthosis

SPIO® Core-MAX® Expedition thoracolumbosacral orthosis

Intervention Type DEVICE

SPIO® Core-MAX® Expedition thoracolumbosacral orthosis use 2 hours per day for 6 months

Control group

Standard Care Therapy option 2: parents may self-select this standard care option of therapy alone

Standard Care Therapy option

Intervention Type OTHER

Standard of care Therapy without the use of trunk orthosis

Interventions

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SPIO® Core-MAX® Expedition thoracolumbosacral orthosis

SPIO® Core-MAX® Expedition thoracolumbosacral orthosis use 2 hours per day for 6 months

Intervention Type DEVICE

Standard Care Therapy option

Standard of care Therapy without the use of trunk orthosis

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Study subjects aged 6 months to 18 months age corrected with abnormal muscle tone
* No previous use of SPIO® or similar Lycra/compression garments
* Assessed by provider as likely to benefit from use of compression garment

Exclusion Criteria

* Non-English speaking
* Inability for family to bring study subject to assessments
* Orthosis or casting that contraindicate SPIO® Core-MAX® during the study period
* Botulinum toxin injections within 3 months, or during study participation
* Having prior orthopedic or neurosurgery surgeries within one year
Minimum Eligible Age

6 Months

Maximum Eligible Age

18 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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SPIO

UNKNOWN

Sponsor Role collaborator

Medical College of Wisconsin

OTHER

Sponsor Role lead

Responsible Party

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Mitchell O'Neill

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mitchell O'Neill, MD

Role: PRINCIPAL_INVESTIGATOR

Medical College of Wisconsin

Locations

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Medical College of Wisconsin/Children's Wisconsin

Milwaukee, Wisconsin, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Mitchell O'Neill, MD

Role: CONTACT

414-266-4771

Sarah Golus

Role: CONTACT

414-955-1923

Facility Contacts

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Mitchell O'Neill, MD

Role: primary

414-266-4771

Sarah Golus

Role: backup

414-955-1923

Other Identifiers

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PRO00048530

Identifier Type: -

Identifier Source: org_study_id

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