Identifying Circadian Rest-Activity Rhythm Disorders in Patients With Advanced Cancer

NCT ID: NCT06023654

Last Updated: 2025-04-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-15

Study Completion Date

2024-05-22

Brief Summary

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Circadian rest-Activity Rhythm disorders (CARDs) are common in patients with cancer, particularly in advanced disease. CARDs are associated with increased symptoms, poorer quality of life, poorer response to anticancer treatments and shorter survival.

The goal of this observational study is to see how common CARDs are in patients with advanced cancer and to characterise their rest and activity patterns in more detail.

A recent study has outlined a standard way to assess and diagnose a CARD.

This study aims to assess patients with advanced cancer for a CARD using a novel screening tool against this newly formed diagnostic criteria. Potentially modifiable risk factors will be considered along with associations between CARDs and symptoms, sleep preferences, sleep quality, daytime sleepiness, quality of life measures and predictors of survival.

Detailed Description

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Conditions

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Cancer Circadian Rhythm Disorders Sleep Disturbance Activity, Motor Accelerometry

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Adult (18 years of age or older)
* Locally advanced or metastatic cancer
* Outpatient
* Ambulatory
* Prognosis of 3 months or more

Exclusion Criteria

* Inpatient
* Shiftworker
* Recent long-haul travel
* Cognitive impairment impacting on ability to complete questionnaires
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Our Lady's Hospice and Care Services

OTHER

Sponsor Role collaborator

University of Dublin, Trinity College

OTHER

Sponsor Role lead

Responsible Party

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Prof Andrew Davies

Professor of Palliative Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Our Lady's Hospice & Care Services

Dublin, , Ireland

Site Status

St James's Hospital

Dublin, , Ireland

Site Status

Countries

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Ireland

Other Identifiers

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1926A

Identifier Type: -

Identifier Source: org_study_id

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