An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan
NCT ID: NCT06023030
Last Updated: 2025-04-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
240 participants
OBSERVATIONAL
2023-07-28
2026-11-30
Brief Summary
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Upadacitinib is a drug approved for the treatment of CD. All study participants will receive upadacitinib as prescribed by their study doctor in accordance with approved local label. Approximately 240 participants will be enrolled in Japan.
Participants will receive upadacitinib as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 64 weeks.
There is expected to be no additional burden for participants in this trial. Study visits may be conducted on-site or virtually as per standard of care.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Upadacitinib
Participants will receive upadacitinib as prescribed by their physician according to local label.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Has been prescribed upadacitinib for CD as per most current local approved label after its approval for CD in Japan.
* Within 14 days from the commencement of upadacitinib induction treatment for CD at the participating institution.
Exclusion Criteria
* Participants for whom upadacitinib is contraindicated.
* Has been treated with upadacitinib for CD before and continue treatment with upadacitinib for CD at the participation to this study.
15 Years
ALL
No
Sponsors
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AbbVie
INDUSTRY
Responsible Party
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Principal Investigators
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ABBVIE INC.
Role: STUDY_DIRECTOR
AbbVie
Locations
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Anjou Kousei Hospital /ID# 261872
Anjo-shi, Aichi-ken, Japan
Handa City Hospital /ID# 270446
Handa, Aichi-ken, Japan
Aichi Medical University Hospital /ID# 261871
Nagakute, Aichi-ken, Japan
Masuko Memorial Hospital /ID# 267420
Nagoya, Aichi-ken, Japan
Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital /ID# 276219
Nagoya, Aichi-ken, Japan
Nagoya City University Hospital /ID# 275588
Nagoya, Aichi-ken, Japan
Toyohashi Municipal Hospital /ID# 274975
Toyohashi, Aichi-ken, Japan
Ieda Hospital /ID# 259754
Toyota-shi, Aichi-ken, Japan
Hachinohe City Hospital /ID# 264183
Hachinohe, Aomori, Japan
Tsujinaka Hospital Kashiwanoha /ID# 262648
Kashiwa-shi, Chiba, Japan
Matsuyama Red Cross Hospital /ID# 266717
Matsuyama, Ehime, Japan
Uwajima City Hospital /ID# 273444
Uwajima, Ehime, Japan
Fukuoka University Chikushi Hospital /ID# 262686
Chikushino-shi, Fukuoka, Japan
Kitakyushu Municipal Medical Center /ID# 276257
Kitakyushu, Fukuoka, Japan
Tobata Kyoritsu Hospital /ID# 273558
Kitakyushu, Fukuoka, Japan
Steel Memorial Yahata Hospital /ID# 272713
Kitakyushu, Fukuoka, Japan
Hidaka Colon Proctology Clinic /ID# 268867
Kurume, Fukuoka, Japan
Hakuai Clinic /ID# 261876
Kurume-shi, Fukuoka, Japan
Ashiya Central Hospital /ID# 275324
Onga-gun, Fukuoka, Japan
Southern Tohoku General Hospital /ID# 270447
Kōriyama, Fukushima, Japan
Sakura Clinic /ID# 268344
Kakamigahara-shi, Gifu, Japan
NHO Fukuyama Medical Center /ID# 261873
Fukuyama-shi, Hiroshima, Japan
JA Hiroshima General Hospital /ID# 264432
Hatsukaichi, Hiroshima, Japan
Kaisei Clinic /ID# 261883
Hiroshima, Hiroshima, Japan
Ako-City Hospital /ID# 271276
Ako, Hyōgo, Japan
Hyogo Prefectural Harima-Himeji General Medical Center /ID# 274528
Himeji, Hyōgo, Japan
Himeji Chuo Hospital /ID# 272714
Himeji, Hyōgo, Japan
Itami City Hospital /ID# 276258
Itami, Hyōgo, Japan
Aoyama Clinic /ID# 262658
Kobe, Hyōgo, Japan
Kobe City Medical Center General Hospital /ID# 270950
Kobe, Hyōgo, Japan
Hyogo Medical University Hospital /ID# 267383
Nishinomiya, Hyōgo, Japan
Kita-Harima Medical Center /ID# 276256
Ono, Hyōgo, Japan
Tsukuba Endoscopy clinic /ID# 261880
Tsukuba, Ibaraki, Japan
National Hospital Organization Kanazawa Medical Center /ID# 268820
Kanazawa, Ishikawa-ken, Japan
Takamatsu Red Cross Hospital /ID# 268823
Takamatsu, Kagawa-ken, Japan
Maeda Hospital /ID# 275554
Takamatsu, Kagawa-ken, Japan
Tokai University Hospital /ID# 270949
Isehara, Kanagawa, Japan
Gokeikai Ofuna Chuo Hospital /ID# 262649
Kamakura-shi, Kanagawa, Japan
Shimizuogimachi Clinic /ID# 276278
Odawara-shi, Kanagawa, Japan
Kitasato University Hospital /ID# 276524
Sagamihara-shi, Kanagawa, Japan
Yokohama Municipal Citizen's Hospital /ID# 267375
Yokohama, Kanagawa, Japan
Inoue Gastroenterology Clinic /ID# 275555
Yokohama, Kanagawa, Japan
Saiseikai Yokohama Tobu Hospital /ID# 264186
Yokohama, Kanagawa, Japan
Chikamori Hospital /ID# 267382
Kochi, Kochi, Japan
Coloproctology Center Takano Hospital /ID# 268868
Kumamoto, Kumamoto, Japan
Japanese Red Cross Kyoto Daiichi Hosital /ID# 262660
Kyoto, Kyoto, Japan
National Hospital Organization Kyoto Medical Center /ID# 265461
Kyoto, Kyoto, Japan
Mie University Hospital /ID# 262656
Tsu, Mie-ken, Japan
Yokkaichi Hazu Medical Center /ID# 260140
Yokkaichi-shi, Mie-ken, Japan
Nagano Municipal Hospital /ID# 262627
Nagano, Nagano, Japan
Honda Internal Medicine and Endoscopy Clinic /ID# 275628
Nagasaki, Nagasaki, Japan
Ishida Clinic of IBD and Gastroenterology /ID# 261884
Ōita, Oita Prefecture, Japan
University of the Ryukyus Hospital /ID# 264430
Ginowan-shi, Okinawa, Japan
Naha City Hospital /ID# 261875
Naha, Okinawa, Japan
Seshimo Gastroy & Procto Clinic /ID# 271658
Ibaraki-shi, Osaka, Japan
Moriguchi Keijinkai Hospital /ID# 268821
Moriguchi, Osaka, Japan
Kinshukai Infusion Clinic /ID# 261332
Osaka, Osaka, Japan
National Hospital Organization Osaka National Hospital /ID# 264230
Osaka, Osaka, Japan
Osaka Metropolitan University Hospital /ID# 273559
Osaka, Osaka, Japan
Tane General Hospital /ID# 268871
Osaka, Osaka, Japan
Osaka Rosai Hospital /ID# 267379
Sakai, Osaka, Japan
Fujita Gastroenterology Hospital /ID# 275410
Takatsuki, Osaka, Japan
Ohmori Toshihide Gastrointestinal Clinic /ID# 276192
Ageo, Saitama, Japan
Saitama Medical Center /ID# 270948
Kawagoe, Saitama, Japan
Tokitokai Tokito clinic /ID# 262661
Saitama-shi, Saitama, Japan
Tokorozawa Proctogic Hospital /ID# 268870
Tokorozawa, Saitama, Japan
Kato Clinic /ID# 262650
Hamamatsu, Shizuoka, Japan
Shizuoka Medical Center /ID# 275551
Shimizu, Shizuoka, Japan
Shizuoka Aoi Clinic /ID# 267376
Shizuoka, Shizuoka, Japan
Saigusa Clinic Of Coloproctolo /ID# 275627
Sizuoka-shi, Shizuoka, Japan
Dokkyo Medical University Hospital /ID# 266710
Mibu, Tochigi, Japan
Saiseikai Utsunomiya Hospital /ID# 261878
Utsunomiya, Tochigi, Japan
Juntendo University Hospital /ID# 265452
Bunkyo-ku, Tokyo, Japan
Ginza Central Clinic /ID# 261881
Chuo-ku, Tokyo, Japan
Koganei Tsurukame Clinic /ID# 271660
Koganei-shi, Tokyo, Japan
Ohori IBD Clinic /ID# 261882
Setagaya-ku, Tokyo, Japan
Shinjuku Tsurukame Clinic /ID# 276485
Shibuya City, Tokyo, Japan
Tokyo Medical University Hospital /ID# 262683
Shinjuku-ku, Tokyo, Japan
Tokyo Women'S Medical University Hospital /ID# 274527
Shinjuku-ku, Tokyo, Japan
The Fraternity Memorial Hospital /ID# 274976
Sumida-ku, Tokyo, Japan
Yokota Memorial Hospital /ID# 266714
Toyama, Toyama, Japan
Wakayama Medical University Hospital /ID# 262685
Wakayama, Wakayama, Japan
Sentohill Hospital /ID# 268869
Ube, Yamaguchi, Japan
Yamanashi Prefectural Central Hospital /ID# 274526
Kofu, Yamanashi, Japan
Fukuiken Saiseikai Hospital /ID# 274835
Fukui, , Japan
Fukushima Red Cross Hospital /ID# 275322
Fukushima, , Japan
Gifu University Hospital /ID# 266711
Gifu, , Japan
Japanease Red Cross Society Himeji Hospital /ID# 275590
Himeji, , Japan
Kagoshima IBD Gastroenterology Clinic /ID# 265505
Kagoshima, , Japan
Kuniyoshi Hospital /ID# 271878
Kochi, , Japan
Saga-Ken Medical Centre Koseikan /ID# 274957
Saga, , Japan
Saitama City Hospital /ID# 266716
Saitama, , Japan
Sapporo Kosei General Hospital /ID# 267374
Sapporo, , Japan
Kitasato University Kitasato Institute Hospital /ID# 268345
Tokyo, , Japan
Tokyo Yamate Medical Center /ID# 275591
Tokyo, , Japan
Teikyo University Hospital /ID# 274525
Tokyo, , Japan
Teikyo University Hospital /ID# 274977
Tokyo, , Japan
Municipal Toyonaka Hospital /ID# 266712
Toyonaka, , Japan
Japanese Red Cross Society - Wakayama Medical Center /ID# 268822
Wakayama, , Japan
Yamagata Prefectural Central Hospital - Yamagata /ID# 268819
Yamagata, , Japan
Yamaguchi Red Cross Hospital /ID# 267381
Yamaguchi, , Japan
Countries
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Central Contacts
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Related Links
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Other Identifiers
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P24-080
Identifier Type: -
Identifier Source: org_study_id
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