SSVEP Evaluation of Brain Function (PRO)

NCT ID: NCT06013566

Last Updated: 2024-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-01

Study Completion Date

2026-01-31

Brief Summary

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The investigational device used in this clinical investigation, the Nurochek PRO System (NCPRO), is a portable electroencephalogram (EEG) headset which delivers a visual stimulus and measures a VEP. The visual stimulus is delivered to the subjects' eyes via light-emitting diodes, and the EEG measures the user's visual-evoked potential. This headset communicates with an application on a computer, which processes the signals and transmits them to a secure cloud server for analysis and storage of the data. Nurochek PRO is a development of the previously FDA cleared Nurochek System.

The primary objective of this clinical investigation was to evaluate the performance of the investigational device (NCPRO) against clinical diagnosis of detection of mild traumatic brain injury (mTBI). The primary endpoint outlined for this study was set at the collection of 100 valid investigational device readings from individuals with concussion and 500 valid investigational device readings from healthy individuals who have had a plausible mechanism of sustaining a concussion, but do not have one. Additionally, readings from healthy individuals are also to be acquired.

The aim of this study was to collect data from 100 readings from individuals with concussion. The initial assumption was that sites would provide players pre-season and make players available for testing post-concussion. In practice, some sites provided player data only post-concussion event (such as medical clinics). Participants were acquired from sporting clubs, medical clinicals and schools.

Detailed Description

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Conditions

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Mild Traumatic Brain Injury

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Baseline

This cohort contains individuals tested at baseline, usually in the pre-season of their sporting season

SSVEP

Intervention Type DEVICE

Non-invasive, non-interventional SSVEP EEG device

Concussed

This cohort contains individuals who have had a concussion, diagnosed by a doctor.

SSVEP

Intervention Type DEVICE

Non-invasive, non-interventional SSVEP EEG device

Suspected Concussion

This cohort contains individuals suspected of having a concussion, but were cleared by a medical professional and do not have a concussion.

SSVEP

Intervention Type DEVICE

Non-invasive, non-interventional SSVEP EEG device

Interventions

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SSVEP

Non-invasive, non-interventional SSVEP EEG device

Intervention Type DEVICE

Other Intervention Names

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Nurochek PRO

Eligibility Criteria

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Inclusion Criteria

* Individuals aged 12 years and older, participating in sport-related activities.

Exclusion Criteria

* Individuals are excluded if they have a history of seizures, history of epilepsy, structural brain injuries, legal blindness, or sensitivity to flashing lights.
Minimum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Headsafe MFG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Craig Donaldson, MBBS

Role: PRINCIPAL_INVESTIGATOR

Principal Investigator

Locations

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Headsafe

Sydney, , Australia

Site Status RECRUITING

Countries

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Australia

Central Contacts

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Dylan Mahony

Role: CONTACT

+61 430 411 438

Facility Contacts

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Dylan Mahony

Role: primary

+61 430 411 438

Other Identifiers

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2018-10-891-PRO

Identifier Type: -

Identifier Source: org_study_id

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