EEG Monitoring for PERFormance Anticipation

NCT ID: NCT03233282

Last Updated: 2025-10-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

169 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-05-30

Study Completion Date

2018-05-31

Brief Summary

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Identify, characterize and then validate electrophysiological markers linking electrophysiological cerebral activity and performance in cognitive and physical fatigability in humans. To do this, noninvasive explorations of electroencephalography (EEG) and magnetoencephalography (MEG) will be carried out under two conditions of different experiments, the first one that induces a cognitive fatigability and the second one that induces physical fatigability.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Cognitive Fatigability

Group Type OTHER

Electroencephalography (EEG) multi-sensor

Intervention Type OTHER

Electrophysiological measurements of cerebral activity will be performed by multi-sensor electroencephalography (EEG), which is a non-invasive method.

Magnetoencephalography (MEG)

Intervention Type OTHER

Electrophysiological measurements of brain activity will be performed by magnetoencephalography (MEG) which is a non-invasive method.

Behavioral Measures

Intervention Type OTHER

The evaluation of cognitive performance will be carried out by means of behavioral measures, push-button type, handling of a mouse or a joystick.

Reaction time measurement

Intervention Type OTHER

The assessment of cognitive performance will be carried out using standard behavioral measures, such as reaction time measurement.

Assessment of physical performance

Intervention Type OTHER

The assessment of physical performance will be based both on bioenergetic measurements and on quantitative data collected in continuous and relative to the effort (eg instantaneous pedaling speed).

Electrooculogram (EOG)

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Electromyogram (EMG)

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Electrocardiogram with 3 leads

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Physical Fatigability

Group Type OTHER

Electroencephalography (EEG) multi-sensor

Intervention Type OTHER

Electrophysiological measurements of cerebral activity will be performed by multi-sensor electroencephalography (EEG), which is a non-invasive method.

Magnetoencephalography (MEG)

Intervention Type OTHER

Electrophysiological measurements of brain activity will be performed by magnetoencephalography (MEG) which is a non-invasive method.

Behavioral Measures

Intervention Type OTHER

The evaluation of cognitive performance will be carried out by means of behavioral measures, push-button type, handling of a mouse or a joystick.

Reaction time measurement

Intervention Type OTHER

The assessment of cognitive performance will be carried out using standard behavioral measures, such as reaction time measurement.

Assessment of physical performance

Intervention Type OTHER

The assessment of physical performance will be based both on bioenergetic measurements and on quantitative data collected in continuous and relative to the effort (eg instantaneous pedaling speed).

Electrooculogram (EOG)

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Electromyogram (EMG)

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Electrocardiogram with 3 leads

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Electrodermogram (EDG)

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Consumption of O2 (VO2)

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Production of CO2 (VCO2)

Intervention Type OTHER

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Interventions

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Electroencephalography (EEG) multi-sensor

Electrophysiological measurements of cerebral activity will be performed by multi-sensor electroencephalography (EEG), which is a non-invasive method.

Intervention Type OTHER

Magnetoencephalography (MEG)

Electrophysiological measurements of brain activity will be performed by magnetoencephalography (MEG) which is a non-invasive method.

Intervention Type OTHER

Behavioral Measures

The evaluation of cognitive performance will be carried out by means of behavioral measures, push-button type, handling of a mouse or a joystick.

Intervention Type OTHER

Reaction time measurement

The assessment of cognitive performance will be carried out using standard behavioral measures, such as reaction time measurement.

Intervention Type OTHER

Assessment of physical performance

The assessment of physical performance will be based both on bioenergetic measurements and on quantitative data collected in continuous and relative to the effort (eg instantaneous pedaling speed).

Intervention Type OTHER

Electrooculogram (EOG)

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Intervention Type OTHER

Electromyogram (EMG)

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Intervention Type OTHER

Electrocardiogram with 3 leads

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Intervention Type OTHER

Electrodermogram (EDG)

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Intervention Type OTHER

Consumption of O2 (VO2)

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Intervention Type OTHER

Production of CO2 (VCO2)

In order to extract artifacts and verify the physical performances of the subjects, under the conditions of physical fatigability, peripheral electrophysiological recordings will be necessary and complementary to meet the objectives set in this study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult subjects, male or female, right-handed or left-handed, from 18 years up to 70 years;
* Having duly completed the entire confidential medical questionnaire;
* Written consent of free, informed and express participation;
* No hearing problems;
* Having normal or corrected vision;
* Affiliation to a Social Security scheme.


* Adult subjects, male or female, right-handed or left-handed, from 18 years up to 35 years;
* Practicing at least five hours of sports per week;
* Presenting a certificate of no contraindication to an exercise test, intense sports practice or an energy sport in competition of the current year;
* Having duly completed the entire confidential medical questionnaire;
* Without cardiovascular or motor disability;
* Without tumoral, inflammatory, cardiac, pulmonary, renal, digestive (malabsorption syndrome) or liver disease;
* Written consent of free, informed and express participation;
* Affiliation to a Social Security scheme.

Exclusion Criteria

* Pregnant women, nursing mothers or those of childbearing age without contraception
* Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of liberty or of liberty
* Persons protected by the law
* Persons who have performed a maximum stress test within 15 days of the date of inclusion,
* In the course of drug treatments against indicated for the protocol (treatment for neurological diseases, psychiatric ...).
* Metal implants incompatible with MRI (for the subjects concerned, see appendices)
* Metallic implants incompatible with the MEG (for the subjects concerned, see appendices)
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Julien JUNG, MD

Role: PRINCIPAL_INVESTIGATOR

Hospices Civils de Lyon

Locations

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Hospices Civils de Lyon, HFME

Bron, , France

Site Status

Countries

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France

References

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Luc Poinsard, Christian Berthomier, Michel Clémençon, Marie Brandewinder, Slim Essid, Cécilia Damon, François Rigaud, Alexis Bénichoux, Emmanuel Maby, Lesly Fornoni, Patrick Bouchet, Pascal Van Beers, Bertrand Massot, Patrice Revol, Thomas Creveaux, Christian Collet, Jérémie Mattout, Vincent Pialoux and Véronique Billat. EEG-Metabolic Coupling and Time Limit at VO2max During Constant-Load Exercise. Journal of Functional Morphology and Kinesiology. 2025, 10, 369.

Reference Type BACKGROUND

Véronique Billat, Christian Berthomier, Michel Clémençon, Marie Brandewinder, Slim Essid, Cécilia Damon, François Rigaud, Alexis Bénichoux, Emmanuel Maby, Lesly Fornoni, Patrick Bouchet , Pascal Van Beers, Bertrand Massot, Patrice Revol, Luc Poinsard, Thomas Creveaux, Christian Collet, Jérémie Mattout and Vincent Pialoux. Electroencephalography Response during an Incremental Test According to the VO2max Plateau Incidence. Applied Sciences. 2024, 14, 5411.

Reference Type BACKGROUND

Seguin P, Maby E, Fouillen M, Otman A, Luaute J, Giraux P, Morlet D, Mattout J. The challenge of controlling an auditory BCI in the case of severe motor disability. J Neuroeng Rehabil. 2024 Jan 18;21(1):9. doi: 10.1186/s12984-023-01289-3.

Reference Type DERIVED
PMID: 38238759 (View on PubMed)

Other Identifiers

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69HCL16_0661

Identifier Type: -

Identifier Source: org_study_id

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