Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported

NCT ID: NCT05984069

Last Updated: 2025-03-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-01

Study Completion Date

2025-12-31

Brief Summary

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After a prolonged stay in Intensive Care Unit (ICU), fatigue is the most common symptom reported by patients in the Post Intensive Care Syndrome (PICS). Other complications have been described, including ICU-acquired weakness, leading to increased morbidity and mortality after discharge. Actually, risk factors associated with post-ICU fatigue self-reported are not really known.

Detailed Description

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Frailty, defined as a decrease in physiological reserves leading to an alteration in the mechanisms of adaptation to stress, increases the incidence of PICS and could therefore be a cause of post-ICU fatigue self-reported.

The aim of this study is to identify a relationship between markers of frailty, ICU-AW, ICU story and the post-ICU fatigue self-reported 6 months discharge in patients with prolonged ICU stays.

Conditions

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Post Intensive Care Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients on etiologies

Patients over 18 admitted in ICU for all etiologies with mechanical ventilation over 5 days or length of stay in ICU over 10 days will be included

observational prospective data collection

Intervention Type OTHER

Collection of data from medical records.

Interventions

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observational prospective data collection

Collection of data from medical records.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with a length of stay in intensive care \> or equal to 7 days, or mechanical ventilation \> or equal to 5 days

Exclusion Criteria

* Scheduled surgery with admission in ICU
* Pregnancy
* Guardianship
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jérôme MOREL, MD PhD

Role: PRINCIPAL_INVESTIGATOR

CHU SAINT-ETIENNE

Locations

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Chu Saint-Etienne

Saint-Etienne, , France

Site Status RECRUITING

Hôpital Privé de la Loire

Saint-Etienne, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Jérôme MOREL, MD PhD

Role: CONTACT

(0)477828553 ext. +33

Nory ELHADJENE, MD

Role: CONTACT

(0)477828553 ext. +33

Facility Contacts

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Jérôme MOREL, MD PhD

Role: primary

(0)4 77 82 85 53 ext. +33

Other Identifiers

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IRBN962022/CHUSTE

Identifier Type: -

Identifier Source: org_study_id

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