HNC: Human Neural Circuits Electrophysiology During Cognition

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE1

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-05

Study Completion Date

2030-09-01

Brief Summary

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The purpose of this study is to understand how ketamine brings about dissociative symptoms.

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Detailed Description

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The goal of this proposed research is to record the effects of ketamine on brain activity to understand the changes that occur during antidepressant therapy and the side effect of dissociation. This research is designed to probe altered cognitive states associated with dissociation, depression, and other neuropsychiatric conditions.

Conditions

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Psychiatric Disorder

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Ketamine

Study participants will receive 0.5mg/kg of ketamine - one single infusion

Group Type EXPERIMENTAL

Ketamine Hydrochloride

Intervention Type DRUG

Ketamine is an FDA-approved dissociative anesthetic.

Interventions

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Ketamine Hydrochloride

Ketamine is an FDA-approved dissociative anesthetic.

Intervention Type DRUG

Other Intervention Names

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Ketalar

Eligibility Criteria

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Inclusion Criteria

* Patient in clinical neuro inpatient units at Stanford Medical Center
* Age \>18 years old
* Female participants are expected to use an effective method of birth control throughout the study which includes: hormonal methods (birth control pills, patches, injections, vaginal ring or implants), barrier methods (condom or diaphragm) used with spermicide, intrauterine device (IUD), or abstinence (no sex)