Impact of Patient Involvement in Alerts Management of Telemonitoring CPAP

NCT ID: NCT05960175

Last Updated: 2025-08-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

556 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-29

Study Completion Date

2026-10-30

Brief Summary

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Adherence to CPAP determines the expected benefits of the treatment. A dose-benefit relationship has been demonstrated for both functional and cardiovascular benefits. The first few days' use of the device are decisive in determining long-term compliance. In this context, daily monitoring of the data teletransmitted means that we can be more responsive to problems of compliance during the first few days of use; the contribution of telemonitoring can be very positive in a context of poor compliance.

In France, compulsory health insurance coverage of CPAP treatment is authorised for patients aged over 16 with clinical symptoms and an AHI ≥15 events per hour and \<30 events/h in patients with severe cardiovascular co-morbidity. These patients are often not very sleepy due to sympathetic hypertonia with a shorter sleep duration. They are at high risk of non-compliance.

The IPIAM study specifically targets a population at cardiovascular risk and at high risk of non-compliance with CPAP treatment. The IPIAM study aims to involve patients in the success of their treatment via remote monitoring and to show that this approach makes it possible to improve the handling of alerts and to participate in the therapeutic support of the patient. Finally, this population also shares the risk of heart rhythm disorders. As part of a cross-disciplinary inter-pathology telemonitoring approach, it also makes sense to screen for cardiac rhythm disorders by wearing a connected watch.

Detailed Description

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IPIAM is a prospective randomized controled study with two arms. Two approaches to telemonitoring will be compared: the standard telemonitoring carried out by the home healthcare provider (standard of care) will be compared with a new approach in which the patient is involved in managing his treatment by collecting vitals and notifying alerts via two connected devices (a connected watch and a mobile application).

The study will comprise 2 phases :

1. an initial interventional, comparative, randomised phase corresponding to the first 4 months of CPAP treatment,
2. an observational period with standard telemonitoring, lasting until the 12th month of treatment.

In this study, all patients will be treated with the same continuous positive airway pressure ventilator (AirSense 11 Autoset, ResMed).

CPAP alerts will be checked by the home healthcare provider's technicians every week and then managed differently depending on the randomisation group.

Each patient will be seen twice in pulmonology consultations, once for the inclusion visit and once 4 months after CPAP initation.

Conditions

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OSA

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard CPAP telemonitoring

Patients are treated with CPAP and the home healthcare provider carries out monitoring in line with current practice (telemonitoring of treatment and regular home visits).

Group Type NO_INTERVENTION

No interventions assigned to this group

New CPAP telemonitoring approach

Patients are treated with CPAP and the home healthcare provider is offering a new approach to remote monitoring in which patients are involved in managing their CPAP treatment using two connected devices (the Scanwatch connected watch + the mobile application Asten\&masanté) in the first 4 months of treatment.

Group Type EXPERIMENTAL

New telemonitoring approach using 2 connected devices : Scanwatch connected watch + Asten&masanté application

Intervention Type DEVICE

The home healthcare provider will monitor the treatment remotely and make home visits, as in the control group. However, in the case of technical alerts concerning CPAP treatment (problems with observance, leaks, residual apneas), the provider will send the patient a notification via the mobile application in order to provide advice/instructions so that the patient can resolve the alert independently. The provider will monitor the resolution of alerts remotely and may contact the patient by telephone or come to your home if necessary.

If the connected watch detects an abnormal heart rhythm at night, the patient receives a notification and can undergo an electrocardiogram.

Interventions

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New telemonitoring approach using 2 connected devices : Scanwatch connected watch + Asten&masanté application

The home healthcare provider will monitor the treatment remotely and make home visits, as in the control group. However, in the case of technical alerts concerning CPAP treatment (problems with observance, leaks, residual apneas), the provider will send the patient a notification via the mobile application in order to provide advice/instructions so that the patient can resolve the alert independently. The provider will monitor the resolution of alerts remotely and may contact the patient by telephone or come to your home if necessary.

If the connected watch detects an abnormal heart rhythm at night, the patient receives a notification and can undergo an electrocardiogram.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult with newly diagnosed OSA (with central apnea index \<5 ev/h), justifying CPAP and with low sleepiness (Epworth score \<11 at inclusion).
* Patient with at least 1 cardiovascular risk factor (obesity, type I or II diabetes with or without treatment, permanent hypertension with or without treatment, heart failure with preserved ejection fraction, valve disease, history of atrial fibrillation, history of ischaemic heart disease, history of stroke).
* Patient with a smartphone and who agrees to use connected objects during the study.
* Signed informed consent form,
* Subject affiliated to a health insurance system, or is a beneficiary.

Exclusion Criteria

* Patients already fitted with a CPAP machine,
* Patients with permanent atrial fibrillation,
* Patients whose state of health is not stable or requires heavy treatment,
* Patients with cognitive problems.
* Patients participating in another intervention research in pulmonology.
* Vulnerable subject
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Slb Pharma

OTHER

Sponsor Role collaborator

Nouvéal

UNKNOWN

Sponsor Role collaborator

Withings

INDUSTRY

Sponsor Role collaborator

Asten Sante

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Arnaud Prigent, Dr

Role: PRINCIPAL_INVESTIGATOR

Polyclinique Saint-Laurent

Locations

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CH Départemental Vendée

La Roche-sur-Yon, France, France

Site Status RECRUITING

AP-HP Hôpital Européen Georges

Paris, France, France

Site Status RECRUITING

CHU Angers - Service de pneumologie

Angers, , France

Site Status RECRUITING

CHU Dijon-Bourgogne

Dijon, , France

Site Status RECRUITING

CH Versailles

Le Chesnay, , France

Site Status RECRUITING

CH Le Mans

Le Mans, , France

Site Status RECRUITING

CHU Nancy

Nancy, , France

Site Status RECRUITING

AP-HP Pitié Salpêtrière

Paris, , France

Site Status RECRUITING

AP-HP Bichat Claude Bernard

Paris, , France

Site Status RECRUITING

Polyclinique Saint-Laurent - Groupe médical de pneumologie

Rennes, , France

Site Status RECRUITING

CHU Rouen - Charles Nicolle

Rouen, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Anne-Laure Sérandour

Role: CONTACT

+33 2 99 12 19 62

Johan Dupuis

Role: CONTACT

+33 7 89 20 75 33

Facility Contacts

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Acya Bizieux, Dr

Role: primary

Sven GÜNTHER, Dr

Role: primary

Frédérique Gagnadoux, Pr

Role: primary

Pauline Sabot, Dr

Role: primary

Alice De Sanctis, Dr

Role: primary

François Goupil, Dr

Role: primary

Ari Chaouat, Pr

Role: primary

Maxime Patout, Dr

Role: primary

Marie-Pia D'Ortho, Pr

Role: primary

Arnaud Prigent, Dr

Role: primary

Marie-Anne Melone, Dr

Role: primary

Other Identifiers

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IPIAM

Identifier Type: -

Identifier Source: org_study_id

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